The E4 allele of Apolipoprotein E (APOE) is associated with both metabolic dysfunction and
a heightened pro-inflammatory response: two findings that may be intrinsically linked …

Background Cerebral glucose hypometabolism is consistently observed in individuals with
Alzheimer’s disease (AD), as well as in young cognitively normal carriers of the Ε4 allele of …

Background The microglial immune response is a significant contributor to Alzheimer’s disease
(AD) pathophysiology and neurodegeneration. Aging microglia accumulate lipid droplets …

Background Metabolic dysfunction and neuroinflammation characterize Alzheimer’s
disease (AD), but it is unclear if these two facets of the disease are linked. The E4 allele of …

Background Metabolic dysfunction and neuroinflammation characterize Alzheimer’s
disease (AD), but it is unclear if these two facets of the disease are linked. The E4 allele of …

Background Compared to the ‘neutral’ E3, the E4 allele of Apolipoprotein E (APOE) confers
up to a 15‐fold increase in Alzheimer’s Disease (AD) risk. Conversely, the neuroprotective …

Current American Thoracic Society (ATS) standards promote the use of race and ethnicity-specific
reference equations for pulmonary function test (PFT) interpretation. There is rising …

… Cathryn T. Lee has received grant funding from the National Institute of Health (T32HL007605).
Ayodeji Adegunsoye has received grant funding from the National Institute of Health (…

Human brains are three times larger, are organized differently, and mature for a longer
period of time than those of our closest living relatives, the chimpanzees. Together, these …

Background: Generalized social anxiety disorder is an early onset, highly chronic, frequently
disabling disorder with a lifetime prevalence of approximately 13%. The goal of the current …