User profiles for Cecilia Icoresi Mazzeo

Cecilia Icoresi Mazzeo

Staff Scientist
Verified email at sanger.ac.uk
Cited by 2464

[HTML][HTML] Single-cell roadmap of human gonadal development

L Garcia-Alonso, V Lorenzi, CI Mazzeo… - Nature, 2022 - nature.com
Gonadal development is a complex process that involves sex determination followed by
divergent maturation into either testes or ovaries 1 . Historically, limited tissue accessibility, a …

[HTML][HTML] Spatial multiomics map of trophoblast development in early pregnancy

…, L Marconato, E Tuck, L Gardner, CI Mazzeo… - Nature, 2023 - nature.com
The relationship between the human placenta—the extraembryonic organ made by the fetus,
and the decidua—the mucosal layer of the uterus, is essential to nurture and protect the …

[HTML][HTML] Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

…, V Kleshchevnikov, A Tarkowska, T Porter, CI Mazzeo… - Nature …, 2021 - nature.com
The endometrium, the mucosal lining of the uterus, undergoes dynamic changes throughout
the menstrual cycle in response to ovarian hormones. We have generated dense single-cell …

Placentation defects are highly prevalent in embryonic lethal mouse mutants

…, E Fineberg, R Wilson, A Murray, CI Mazzeo… - Nature, 2018 - nature.com
Large-scale phenotyping efforts have demonstrated that approximately 25–30% of mouse
gene knockouts cause intrauterine lethality. Analysis of these mutants has largely focused on …

[HTML][HTML] Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice

…, A Galli, C Tudor, E Tuck, CI Mazzeo… - Wellcome open …, 2016 - ncbi.nlm.nih.gov
Background: Identifying genes that are essential for mouse embryonic development and
survival through term is a powerful and unbiased way to discover possible genetic determinants …

An integrated single-cell reference atlas of the human endometrium

…, R Petryszak, C Sancho-Serra, A Oszlanczi, CI Mazzeo… - bioRxiv, 2023 - biorxiv.org
The human endometrium, the inner lining of the uterus, exhibits complex, dynamic changes
throughout the menstrual cycle in response to ovarian hormones. Aberrant response of …

[HTML][HTML] TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing Zfp423 during corticogenesis

…, B Di Stefano, G Colasante, C Icoresi-Mazzeo… - Developmental …, 2018 - Elsevier
During cerebral cortex development, neural progenitors are required to elaborate a variety
of cell differentiation signals to which they are continuously exposed. RA acid is a potent …

The Col4a2em1(IMPC)Wtsi mouse line: lessons from the Deciphering the Mechanisms of Developmental Disorders program

…, A Galli, C Tudor, E Tuck, C Icoresi-Mazzeo… - Biology …, 2019 - journals.biologists.com
The Deciphering the Mechanisms of Developmental Disorders (DMDD) program uses a
systematic and standardised approach to characterise the phenotype of embryos stemming from …

Spatially resolved single-cell multiomics map of human trophoblast differentiation in early pregnancy

…, L Marconato, E Tuck, L Gardner, CI Mazzeo… - bioRxiv, 2022 - biorxiv.org
The relationship between the human placenta, the extraembryonic organ built by the fetus,
and the decidua, the mucosal layer of the uterus, is essential to nurture and protect the fetus …

Author Correction: Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

…, V Kleshchevnikov, A Tarkowska, T Porter, CI Mazzeo… - nature genetics, 2023 - nature.com
In the version of this article initially published,“European Research Council grant no.
853546” was missing from the Acknowledgements section. The error has been corrected in …