[HTML][HTML] Detection of diverse carbapenem and multidrug resistance genes and high-risk strain types among carbapenem non-susceptible clinical isolates of target …

L Musila, C Kyany'a, R Maybank, J Stam, V Oundo… - PLoS …, 2021 - journals.plos.org
Carbapenem-resistant gram-negative bacteria are an increasingly significant clinical threat
globally. This risk may be underestimated in Kenya as only four carbapenemase genes in …

[HTML][HTML] Phenotypic and genotypic characterization of clinical Staphylococcus aureus isolates from Kenya

C Kyany'a, J Nyasinga, D Matano, V Oundo, S Wacira… - BMC microbiology, 2019 - Springer
Background The increase and spread of virulent-outbreak associated, methicillin and
vancomycin resistant (MRSA/VRSA) Staphylococcus aureus require a better understanding of the …

[HTML][HTML] Genetic Diversity, Distribution, and Genomic Characterization of Antibiotic Resistance and Virulence of Clinical Pseudomonas aeruginosa Strains in Kenya

S Kiyaga, C Kyany'a, AW Muraya, HJ Smith… - Frontiers in …, 2022 - frontiersin.org
Pseudomonas aeruginosa is a leading cause of nosocomial infections worldwide. It can
produce a range of debilitating infections, have a propensity for developing antimicrobial …

[HTML][HTML] Antimicrobial Resistance and Virulence Characteristics of Klebsiella pneumoniae Isolates in Kenya by Whole-Genome Sequencing

A Muraya, C Kyany'a, S Kiyaga, HJ Smith, C Kibet… - Pathogens, 2022 - mdpi.com
Klebsiella pneumoniae is a globally significant opportunistic pathogen causing healthcare-associated
and community-acquired infections. This study examined the epidemiology and …

[HTML][HTML] Determination of Enterococcus faecalis and Enterococcus faecium Antimicrobial Resistance and Virulence Factors and Their Association with Clinical and …

…, E Odoyo, D Matano, F Tiria, C Kyany'a… - Journal of …, 2022 - hindawi.com
Background. Enterococci are clinically significant because of their increasing antibiotic
resistance and their ability to cause severe infections due to an arsenal of virulence genes. Few …

[HTML][HTML] High Prevalence of Multidrug-Resistant Clostridioides difficile Following Extensive Use of Antimicrobials in Hospitalized Patients in Kenya

…, G Revathi, B Kullin, M Burugu, C Kyany'a… - Frontiers in cellular …, 2021 - frontiersin.org
Introduction Clostridioides difficile is a neglected pathogen in many African countries as it is
generally not regarded as one of the major contributors toward the diarrheal disease burden …

[HTML][HTML] Ten thousand-fold higher than acceptable bacterial loads detected in kenyan hospital environments: Targeted approaches to reduce contamination levels

…, M Georges, F Tiria, S Wahome, C Kyany'a… - International Journal of …, 2021 - mdpi.com
Microbial monitoring of hospital surfaces can help identify target areas for improved infection
prevention and control (IPCs). This study aimed to determine the levels and variations in …

[HTML][HTML] First report of Entamoeba moshkovskii in human stool samples from symptomatic and asymptomatic participants in Kenya

C Kyany'a, F Eyase, E Odundo, E Kipkirui… - Tropical diseases, travel …, 2019 - Springer
Entamoeba moshkovskii is a member of the Entamoeba complex and a colonizer of the
human gut. We used nested polymerase chain reaction (PCR) to differentiate Entamoeba …

Colistin Resistance Gene mcr-8 in a High-Risk Sequence Type 15 Klebsiella pneumoniae Isolate from Kenya

C Kyany'a, L Musila - Microbiology Resource Announcements, 2020 - Am Soc Microbiol
The emergence and rise of mobile colistin resistance genes are of great global concern due
to the ease of transfer of resistance to other bacteria. This report describes the genome of a …

[HTML][HTML] Assessment of independent comorbidities and comorbidity measures in predicting healthcare facility-onset Clostridioides difficile infection in Kenya

…, O Anzala, B Kullin, R Ofwete, C Kyany'a… - PLOS Global Public …, 2022 - journals.plos.org
Introduction Clostridioides difficile is primarily associated with hospital-acquired diarrhoea.
The disease burden is aggravated in patients with comorbidities due to increased likelihood …