User profiles for Cecilia Morgantini

Cecilia Morgantini

MD, PhD - Karolinska Institutet
Verified email at sssup.it
Cited by 2030

[HTML][HTML] A subset of Kupffer cells regulates metabolism through the expression of CD36

…, XM Zhang, N Ang, P Chen, C Morgantini… - Immunity, 2021 - cell.com
Tissue macrophages are immune cells whose phenotypes and functions are dictated by origin
and niches. However, tissues are complex environments, and macrophage heterogeneity …

Pharmacological targeting of the atherogenic dyslipidemia complex: the next frontier in CVD prevention beyond lowering LDL cholesterol

C Xiao, S Dash, C Morgantini, RA Hegele, GF Lewis - Diabetes, 2016 - Am Diabetes Assoc
Notwithstanding the effectiveness of lowering LDL cholesterol, residual CVD risk remains in
high-risk populations, including patients with diabetes, likely contributed to by non-LDL lipid …

Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes

C Morgantini, A Natali, B Boldrini, S Imaizumi… - Diabetes, 2011 - Am Diabetes Assoc
OBJECTIVE In mice, 4F, an apolipoprotein AI mimetic peptide that restores HDL function,
prevents diabetes-induced atherosclerosis. We sought to determine whether HDL function is …

New insights into the regulation of chylomicron production

S Dash, C Xiao, C Morgantini… - Annual review of …, 2015 - annualreviews.org
Dietary lipids are efficiently absorbed by the small intestine, incorporated into triglyceride-rich
lipoproteins (chylomicrons), and transported in the circulation to various tissues. Intestinal …

Intranasal insulin suppresses endogenous glucose production in humans compared with placebo in the presence of similar venous insulin concentrations

S Dash, C Xiao, C Morgantini, K Koulajian… - Diabetes, 2015 - Am Diabetes Assoc
Intranasal insulin (INI) has been shown to modulate food intake and food-related activity in
the central nervous system in humans. Because INI increases insulin concentration in the …

High-dose resveratrol treatment for 2 weeks inhibits intestinal and hepatic lipoprotein production in overweight/obese men

S Dash, C Xiao, C Morgantini, L Szeto… - … , and vascular biology, 2013 - Am Heart Assoc
Objective— Overproduction of hepatic apolipoprotein B (apoB)-100 containing very low-density
lipoprotein particles and intestinal apoB-48 containing chylomicrons contributes to …

Liver macrophages regulate systemic metabolism through non-inflammatory factors

C Morgantini, J Jager, X Li, L Levi, V Azzimato… - Nature …, 2019 - nature.com
Liver macrophages (LMs) have been proposed to contribute to metabolic disease through
secretion of inflammatory cytokines. However, anti-inflammatory drugs lead to only modest …

Glucagon-like peptide-2 regulates release of chylomicrons from the intestine

S Dash, C Xiao, C Morgantini, PW Connelly… - Gastroenterology, 2014 - Elsevier
Background & Aims The intestine efficiently incorporates and rapidly secretes dietary fat as
chylomicrons (lipoprotein particles comprising triglycerides, phospholipids, cholesterol, and …

Isolation of Kupffer cells and hepatocytes from a single mouse liver

M Aparicio-Vergara, M Tencerova, C Morgantini… - Alpha-1 Antitrypsin …, 2017 - Springer
Liver perfusion is a common technique used to isolate parenchymal and non-parenchymal
liver cells for in vitro experiments. This method allows hepatic cells to be separated based on …

[HTML][HTML] Hepatic miR-144 drives fumarase activity preventing NRF2 activation during obesity

V Azzimato, P Chen, E Barreby, C Morgantini, L Levi… - Gastroenterology, 2021 - Elsevier
Background and Aims Oxidative stress plays a key role in the development of metabolic
complications associated with obesity, including insulin resistance and the most common …