User profiles for Cecilia Winata
Cecilia Lanny WinataLab Leader, International Institute of Molecular and Cell Biology in Warsaw Verified email at iimcb.gov.pl Cited by 2005 |
Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition
Maternally deposited mRNAs direct early development before the initiation of zygotic
transcription during mid-blastula transition (MBT). To study mechanisms regulating this …
transcription during mid-blastula transition (MBT). To study mechanisms regulating this …
[PDF][PDF] Prepatterning of developmental gene expression by modified histones before zygotic genome activation
A hallmark of anamniote vertebrate development is a window of embryonic transcription-independent
cell divisions before onset of zygotic genome activation (ZGA). Chromatin …
cell divisions before onset of zygotic genome activation (ZGA). Chromatin …
[HTML][HTML] Development of zebrafish swimbladder: The requirement of Hedgehog signaling in specification and organization of the three tissue layers
CL Winata, S Korzh, I Kondrychyn, W Zheng… - Developmental …, 2009 - Elsevier
The swimbladder is a hydrostatic organ in fish postulated as a homolog of the tetrapod lung.
While lung development has been well studied, the molecular mechanism of swimbladder …
While lung development has been well studied, the molecular mechanism of swimbladder …
[HTML][HTML] Requirement of vasculogenesis and blood circulation in late stages of liver growth in zebrafish
S Korzh, X Pan, M Garcia-Lecea, CL Winata… - BMC developmental …, 2008 - Springer
Background Early events in vertebrate liver development have been the major focus in
previous studies, however, late events of liver organogenesis remain poorly understood. Liver …
previous studies, however, late events of liver organogenesis remain poorly understood. Liver …
[HTML][HTML] Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression …
Background Mercury is a prominent environmental contaminant that causes detrimental
effects to human health. Although the liver has been known to be a main target organ, there is …
effects to human health. Although the liver has been known to be a main target organ, there is …
[HTML][HTML] Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements
Zebrafish, a popular organism for studying embryonic development and for modeling human
diseases, has so far lacked a systematic functional annotation program akin to those in …
diseases, has so far lacked a systematic functional annotation program akin to those in …
[HTML][HTML] Wnt signaling is required for early development of zebrafish swimbladder
Background Wnt signaling plays critical roles in mammalian lung development. However,
Wnt signaling in the development of the zebrafish swimbladder, which is considered as a …
Wnt signaling in the development of the zebrafish swimbladder, which is considered as a …
[PDF][PDF] Chromatin states of developmentally-regulated genes revealed by DNA and histone methylation patterns in zebrafish embryos
Embryo development proceeds from a cascade of gene activation and repression events
controlled by epigenetic modifications of DNA and histones. Little is known about epigenetic …
controlled by epigenetic modifications of DNA and histones. Little is known about epigenetic …
Transcriptome kinetics of arsenic-induced adaptive response in zebrafish liver
Arsenic is a prominent environmental toxicant and carcinogen; however, its molecular
mechanism of toxicity and carcinogenicity remains poorly understood. In this study, we performed …
mechanism of toxicity and carcinogenicity remains poorly understood. In this study, we performed …
The translational regulation of maternal mrna s in time and space
Since their discovery, the study of maternal mRNA s has led to the identification of mechanisms
underlying their spatiotemporal regulation within the context of oogenesis and early …
underlying their spatiotemporal regulation within the context of oogenesis and early …