Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions
…, J Rademacher, RD Bagshaw, C Wortmann… - Nature cell …, 2020 - nature.com
Rho GTPases are central regulators of the cytoskeleton and, in humans, are controlled by
145 multidomain guanine nucleotide exchange factors (RhoGEFs) and GTPase-activating …
145 multidomain guanine nucleotide exchange factors (RhoGEFs) and GTPase-activating …
[PDF][PDF] Direct observation of cell-cycle-dependent interactions between CTCF and chromatin
H Agarwal, M Reisser, C Wortmann, JCM Gebhardt - Biophysical journal, 2017 - cell.com
The three-dimensional arrangement of chromatin encodes regulatory traits important for
nuclear processes such as transcription and replication. Chromatin topology is in part mediated …
nuclear processes such as transcription and replication. Chromatin topology is in part mediated …
Spatial organization of Rho GTPase signaling by RhoGEF/RhoGAP proteins
…, G Mbamalu, M Tucholska, L Spatt, C Wortmann… - Biorxiv, 2018 - biorxiv.org
Rho GTPases control cell shape formation and thus fundamental physiological processes in
all eukaryotes. Their functions are regulated by 145 RhoGEF and RhoGAP multi-domain …
all eukaryotes. Their functions are regulated by 145 RhoGEF and RhoGAP multi-domain …
[PDF][PDF] Perm-waved human hair: a thermorheologically complex shape memory composite
A "permanent" bent shape can be imposed on a straight human hair by a two-stage
reduction/oxidation (perm-waving) process. The process relies on the molecular level on sulfhydryl/…
reduction/oxidation (perm-waving) process. The process relies on the molecular level on sulfhydryl/…
[HTML][HTML] pH-equilibration of human hair: Kinetics and pH-dependence of the partition ratios for H+− and OH−-ions based on a Freundlich isotherm
FJ Wortmann, K Hardie, N Schellenberg, C Jones… - Biophysical …, 2023 - Elsevier
Hair is an insoluble, fibrous, α-keratinous, protein composite material, providing outer
coverage, eg, for mammals. In the context of a wider study on the effects of pH on human hair …
coverage, eg, for mammals. In the context of a wider study on the effects of pH on human hair …
Neutropenia and intellectual disability are hallmarks of biallelic and de novo CLPB deficiency
SB Wortmann, S Ziętkiewicz, S Guerrero-Castillo… - Genetics in …, 2021 - nature.com
Purpose To investigate monoallelic CLPB variants. Pathogenic variants in many genes cause
congenital neutropenia. While most patients exhibit isolated hematological involvement, …
congenital neutropenia. While most patients exhibit isolated hematological involvement, …
[HTML][HTML] Textile materials inspired by structural colour in nature
The concept of mimicking structural colour in nature as an alternative to traditional textile
coloration techniques would reduce dependency on dyes, pigments and vast quantities of …
coloration techniques would reduce dependency on dyes, pigments and vast quantities of …
The Effects of Humidity on Hairstyles: Analysis of the mechanical properties of styling polymers
…, G Wortmann, FJ Wortmann - Proc 22nd …, 2021 - research.manchester.ac.uk
The aim of this study is to extend the knowledge gained through the dynamic humidity curl
retention (DHCR) to determine the influence of the polymers in the composite (polymer/hair) …
retention (DHCR) to determine the influence of the polymers in the composite (polymer/hair) …
High-strain stress relaxation: probing the main structural components in the cortex of human hair
…, G Wortmann, C Jones, K Lee, FJ Wortmann - 2021 - e-space.mmu.ac.uk
The relation between the main cortical structures in hair (IFs & matrix) and its mechanical
properties has been studied for many years. Beyond fundamentals aspects, this was also done …
properties has been studied for many years. Beyond fundamentals aspects, this was also done …
Liquid Crystals Science and Technology: Editor's Themed Collection
C Jones, FJ Wortmann, H Gleeson, S Yates - 2022 - research.manchester.ac.uk
Welcome to this themed collection on “Liquid Crystals Science and Technology”, guest
edited by Dr Giacomo Saielli (Italian National Research Council and University of Padova).
edited by Dr Giacomo Saielli (Italian National Research Council and University of Padova).