Genetic Network Analyzer: qualitative simulation of genetic regulatory networks
Motivation: The study of genetic regulatory networks has received a major impetus from the
recent development of experimental techniques allowing the measurement of patterns of …
recent development of experimental techniques allowing the measurement of patterns of …
ExPASy: SIB bioinformatics resource portal
…, E Gasteiger, A Grosdidier, C Hernandez… - Nucleic acids …, 2012 - academic.oup.com
ExPASy ( http://www.expasy.org ) has worldwide reputation as one of the main bioinformatics
resources for proteomics. It has now evolved, becoming an extensible and integrative …
resources for proteomics. It has now evolved, becoming an extensible and integrative …
[HTML][HTML] The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis
P Huebener, JP Pradere, C Hernandez… - The Journal of …, 2019 - Am Soc Clin Investig
In contrast to microbially triggered inflammation, mechanisms promoting sterile inflammation
remain poorly understood. Damage-associated molecular patterns (DAMPs) are …
remain poorly understood. Damage-associated molecular patterns (DAMPs) are …
Qualitative simulation of genetic regulatory networks using piecewise-linear models
In order to cope with the large amounts of data that have become available in genomics,
mathematical tools for the analysis of networks of interactions between genes, proteins, and …
mathematical tools for the analysis of networks of interactions between genes, proteins, and …
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1
Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we
identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a …
identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a …
Damage-associated molecular patterns in cancer: a double-edged sword
Damage-associated molecular patterns (DAMPs) are released in response to cell death
and stress, and are potent triggers of sterile inflammation. Recent evidence suggests that …
and stress, and are potent triggers of sterile inflammation. Recent evidence suggests that …
RSAT 2015: regulatory sequence analysis tools
…, C Hernandez… - Nucleic acids …, 2015 - academic.oup.com
RSAT (Regulatory Sequence Analysis Tools) is a modular software suite for the analysis of
cis-regulatory elements in genome sequences. Its main applications are (i) motif discovery, …
cis-regulatory elements in genome sequences. Its main applications are (i) motif discovery, …
Qualitative simulation of the initiation of sporulation in Bacillus subtilis
Under conditions of nutrient deprivation, the Gram positive soil bacterium Bacillus subtilis
can abandon vegetative growth and form a dormant, environmentally-resistant spore instead. …
can abandon vegetative growth and form a dormant, environmentally-resistant spore instead. …
Genomics in the long-read sequencing era
…, R Ouazahrou, C Thermes, C Hernandez - Trends in Genetics, 2023 - cell.com
Long-read sequencing (LRS) technologies have provided extremely powerful tools to explore
genomes. While in the early years these methods suffered technical limitations, they have …
genomes. While in the early years these methods suffered technical limitations, they have …
Production of infectious hepatitis C virus in primary cultures of human adult hepatocytes
…, L Aoudjehane, M Carrière, S Zaïdi, C Hernandez… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Although hepatitis C virus (HCV) can be grown in the
hepatocarcinoma-derived cell line Huh-7, a cell-culture model is needed that supports its complete, …
hepatocarcinoma-derived cell line Huh-7, a cell-culture model is needed that supports its complete, …