Pseudomonas aeruginosa: all roads lead to resistance
EBM Breidenstein, C de la Fuente-Núñez… - Trends in …, 2011 - cell.com
Pseudomonas aeruginosa is often resistant to multiple antibiotics and consequently has
joined the ranks of ‘superbugs' due to its enormous capacity to engender resistance. It …
joined the ranks of ‘superbugs' due to its enormous capacity to engender resistance. It …
The value of antimicrobial peptides in the age of resistance
…, C Pinilla, C de La Fuente-Nunez… - The lancet infectious …, 2020 - thelancet.com
Accelerating growth and global expansion of antimicrobial resistance has deepened the need
for discovery of novel antimicrobial agents. Antimicrobial peptides have clear advantages …
for discovery of novel antimicrobial agents. Antimicrobial peptides have clear advantages …
Bacterial biofilm development as a multicellular adaptation: antibiotic resistance and new therapeutic strategies
C De la Fuente-Núñez, F Reffuveille… - Current opinion in …, 2013 - Elsevier
… Author links open overlay panel César de la Fuente-Núñez , Fany Reffuveille , Lucía
Fernández , Robert EW Hancock … de la Fuente-Núñez, REW Hancock …
Fernández , Robert EW Hancock … de la Fuente-Núñez, REW Hancock …
[HTML][HTML] Broad-spectrum anti-biofilm peptide that targets a cellular stress response
C De la Fuente-Núñez, F Reffuveille, EF Haney… - PLoS …, 2014 - journals.plos.org
Bacteria form multicellular communities known as biofilms that cause two thirds of all
infections and demonstrate a 10 to 1000 fold increase in adaptive resistance to conventional …
infections and demonstrate a 10 to 1000 fold increase in adaptive resistance to conventional …
Leveraging artificial intelligence in the fight against infectious diseases
Despite advances in molecular biology, genetics, computation, and medicinal chemistry,
infectious disease remains an ominous threat to public health. Addressing the challenges …
infectious disease remains an ominous threat to public health. Addressing the challenges …
Next-generation precision antimicrobials: towards personalized treatment of infectious diseases
Highlights • Precision antimicrobials represent a novel approach for treating infectious
diseases. • The role of the microbiota in health and disease is indisputable and so is the need to …
diseases. • The role of the microbiota in health and disease is indisputable and so is the need to …
[PDF][PDF] D-enantiomeric peptides that eradicate wild-type and multidrug-resistant biofilms and protect against lethal Pseudomonas aeruginosa infections
C De La Fuente-Núñez, F Reffuveille, SC Mansour… - Chemistry & biology, 2015 - cell.com
In many infections, bacteria form surface-associated communities known as biofilms that are
substantially more resistant to antibiotics than their planktonic counterparts. Based on the …
substantially more resistant to antibiotics than their planktonic counterparts. Based on the …
Development of molecularly imprinted polymers to block quorum sensing and inhibit bacterial biofilm formation
Bacterial biofilms are responsible for most clinical infections and show increased antimicrobial
resistance. In this study, molecularly imprinted polymers (MIPs) were developed to …
resistance. In this study, molecularly imprinted polymers (MIPs) were developed to …
A broad-spectrum antibiofilm peptide enhances antibiotic action against bacterial biofilms
F Reffuveille, C De La Fuente-Nú̃nez… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Biofilm-related infections account for at least 65% of all human infections, but there are no
available antimicrobials that specifically target biofilms. Their elimination by available …
available antimicrobials that specifically target biofilms. Their elimination by available …
3D printing of living responsive materials and devices
…, TC Tang, E Tham, C de la Fuente‐Nunez… - Advanced …, 2018 - Wiley Online Library
3D printing has been intensively explored to fabricate customized structures of responsive
materials including hydrogels, liquid‐crystal elastomers, shape‐memory polymers, and …
materials including hydrogels, liquid‐crystal elastomers, shape‐memory polymers, and …