A sedentary lifestyle has been linked to a number of metabolic disorders that have been
associated with sub-optimal mitochondrial characteristics and an increased risk of premature …

Mitochondrial defects are implicated in multiple diseases and aging. Exercise training is an
accessible, inexpensive therapeutic intervention that can improve mitochondrial …

Prescribing the frequency, duration, or volume of training is simple as these factors can be
altered by manipulating the number of exercise sessions per week, the duration of each …

Background While there is agreement that exercise is a powerful stimulus to increase both
mitochondrial function and content, we do not know the optimal training stimulus to maximise …

Exercise training has been associated with increased mitochondrial content and respiration.
However, no study to date has compared in parallel how training at different intensities …

It is well established that different types of exercise can provide a powerful stimulus for
mitochondrial biogenesis. However, there are conflicting findings in the literature, and a …

Physical inactivity represents the fourth leading risk factor for mortality, and it has been
linked with a series of chronic disorders, the treatment of which absorbs ~ 85% of healthcare …

Gene expression analysis by quantitative PCR in skeletal muscle is routine in exercise
studies. The reproducibility and reliability of the data fundamentally depend on how the …

Increased mitochondrial content and respiration have both been reported after exercise
training. However, no study has directly compared how different training volumes influence …

Background Exercise promotes numerous phenotypic adaptations in skeletal muscle that
contribute to improved function and metabolic capacity. An emerging body of evidence …