Multipotential mesenchymal stem cells from femoral bone marrow near the site of osteonecrosis

…, H Chiang, LL Chiou, MH Chen, CH Hsieh… - Stem …, 2003 - academic.oup.com
Stem cell-based therapies for degenerative disorders and injuries are promising in the new
era. Multipotential mesenchymal stem cells (MSCs) from bone marrow (BM) are on the …

Antithyroid drug‐related hepatotoxicity in hyperthyroidism patients: a population‐based cohort study

…, TY Huang, CL Chu, CH Hsieh - British journal of …, 2014 - Wiley Online Library
Aims The evidence of hepatotoxicity of antithyroid drugs ( ATDs ) is limited to case reports or
spontaneous reporting. This study aimed to quantify the incidence and comparative risks of …

Genome-wide association study in a Chinese population with diabetic retinopathy

…, E Ipp, SY Lin, X Guo, CH Hsieh… - Human molecular …, 2013 - academic.oup.com
Diabetic retinopathy (DR) is a leading cause of preventable blindness in adults. To identify
genetic contributions in DR, we studied 2071 type 2 diabetics. We first conducted a genome-…

Association and interaction analyses of genetic variants in ADIPOQ, ENPP1, GHSR, PPARγ and TCF7L2 genes for diabetic nephropathy in a Taiwanese population …

LSH Wu, CH Hsieh, D Pei, YJ Hung… - Nephrology Dialysis …, 2009 - academic.oup.com
Background. Diabetic nephropathy (DN) is a common microvascular complication of
diabetes. In this study, we aimed to explore both primary effects of single-locus and multilocus …

Serum uric acid level as an indicator for CKD regression and progression in patients with type 2 diabetes mellitus—a 4.6‐year cohort study

…, CC Lei, KC Lin, DM Chang, CH Hsieh… - Diabetes/Metabolism …, 2016 - Wiley Online Library
Background To investigate the association of serum uric acid level with renal function change
in patients with type 2 diabetes mellitus (T2DM). Methods T2DM patients who had been …

Circulating pro-inflammatory cytokines and adiponectin in young men with type 2 diabetes

SC Su, D Pei, CH Hsieh, FC Hsiao, CZ Wu, YJ Hung - Acta diabetologica, 2011 - Springer
This study was designed to investigate plasma circulating pro-inflammatory cytokines,
adiponectin and high-sensitive C-reactive protein (hsCRP) in young men with type 2 diabetes. …

[HTML][HTML] Combination COX-2 inhibitor and metformin attenuate rate of joint replacement in osteoarthritis with diabetes: A nationwide, retrospective, matched-cohort …

…, CH Hsieh, YJ Hung, FH Lin, CH Tsao, PS Hsieh… - PLoS …, 2018 - journals.plos.org
Background Osteoarthritis (OA) is the most common form of arthritis associated with an
increased prevalence of type 2 diabetes mellitus (T2DM), however their impact on decreasing …

Insulin sensitivity, proinflammatory markers and adiponectin in young males with different subtypes of depressive disorder

YJ Hung, CH Hsieh, YJ Chen, D Pei… - Clinical …, 2007 - Wiley Online Library
Objective This study was designed to evaluate insulin sensitivity, proinflammatory markers
and adiponectin concentration in young males with different subtypes of depressive disorder. …

[HTML][HTML] Proteomic analysis of osteoarthritic chondrocyte reveals the hyaluronic acid-regulated proteins involved in chondroprotective effect under oxidative stress

CJ Yu, CJ Ko, CH Hsieh, CT Chien, LH Huang… - Journal of …, 2014 - Elsevier
Osteoarthritis (OA), the most common type of arthritis, is a degenerative joint disease. Oxidative
stress is well known to play important roles in cartilage degradation and pathogenesis of …

[HTML][HTML] High-molecular-weight hyaluronic acid inhibits IL-1β-induced synovial inflammation and macrophage polarization through the GRP78-NF-κB signaling …

…, SC Su, CL Huang, JS Liu, CH Lu, CH Hsieh… - International journal of …, 2021 - mdpi.com
Recent evidence has suggested that synovial inflammation and macrophage polarization
were involved in the pathogenesis of osteoarthritis (OA). Additionally, high-molecular-weight …