Non-specific lipid-transfer proteins (nsLTPs) are involved in the movement of phospholipids,
glycolipids, fatty acids, and steroids between membranes. Several structures of plant …

SARS-CoV-2 Nsp15 is a uridine-specific endoribonuclease with C-terminal catalytic domain
belonging to the EndoU family that is highly conserved in coronaviruses. As …

Cyclic diguanylate (or bis-(3′–5′) cyclic dimeric guanosine monophosphate; c-di-GMP) is
a ubiquitous second messenger that regulates diverse cellular functions, including motility, …

DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA
replication, repair and recombination, utilizing either ATP or NAD+ as a cofactor. Despite the …

Glutaminases belong to the large superfamily of serine-dependent β-lactamases and
penicillin-binding proteins, and they catalyze the hydrolytic deamidation of l-glutamine to l-…

The TonB-dependent complex of Gram-negative bacteria couples the inner membrane proton
motive force to the active transport of iron·siderophore and vitamin B 12 across the outer …

To the editor: Obtaining diffraction-quality crystals is a major bottleneck in protein X-ray
crystallography. For example, the current success rate for protein structure solution at the …

α-Amylases (α-1,4-glucan-4-glucanohydrolase, EC3.2.1.1) catalyze the cleavage of α-1, 4-glucosidic
linkages of starch components, glycogen, and various oligosaccharides. …

Mitochondria are critical to cellular and organismal health. To prevent damage, mitochondria
have evolved protein quality control machines to survey and maintain the mitochondrial …

Interleukin-19 (IL-19) is a novel cytokine that was initially identified during a sequence data
base search aimed at finding potential IL-10 homologs. IL-19 shares a receptor complex with …