Modern humans have occupied almost all possible environments globally since exiting Africa
about 100,000 years ago. Both behavioral and biological adaptations have contributed to …

Tibetans live on the highest plateau in the world, their current population size is approximately
5 million, and most of them live at an altitude exceeding 3,500 m. Therefore, the Tibetan …

China’s Southwest region is home to the 56 ethnic groups living in China. 13 Ethnicity not
only represents genetic diversity but also characterizes strong local identities for work and …

Tibetans are well adapted to high-altitude hypoxic conditions, and in recent genome-wide
scans, many candidate genes have been reported involved in the physiological response to …

Tibetans are well adapted to the hypoxic environments at high altitude, yet the molecular
mechanism of this adaptation remains elusive. We reported comprehensive genetic and …

High-altitude adaptation of Tibetans represents a remarkable case of natural selection during
recent human evolution. Previous genome-wide scans found many non-coding variants …

Yak is one of the largest native mammalian species at the Himalayas, the highest plateau
area in the world with an average elevation of >4,000 m above the sea level. Yak is well …

The adaptation of Tibetans to high-altitude environments has been studied extensively.
However, the direct assessment of evolutionary adaptation, ie, the reproductive fitness of …

Tibetans are well adapted to high‐altitude environments. Among the adaptive traits in Tibetans,
the relatively low hemoglobin level is considered a blunted erythropoietic response to …

Our aim was to clarify whether substitution of cytosine for adenine at position 1166 (A1166C)
polymorphism of the angiotensin II type 1 receptor (AT1R) gene is associated with …