The purpose of this work was to evaluate the effect of androgen receptor (AR) inhibition on
prostate-specific membrane antigen (PSMA) uptake imaged using 68 Ga-PSMA-11 PET in a …

We previously reported the synthesis of gadolinium-based nanoparticles (NPs) denoted
AGuIX (activation and guiding of irradiation by X-ray) NPs and demonstrated their potential as …

New, ultrasmall nanoparticles with sizes below 5 nm have been obtained. These small rigid
platforms (SRP) are composed of a polysiloxane matrix with DOTAGA (1,4,7,10‐…

AGuIX ® are sub-5 nm nanoparticles made of a polysiloxane matrix and gadolinium
chelates. This nanoparticle has been recently accepted in clinical trials in association with …

High sensitivity imaging tools could provide a more holistic view of target antigen expression
to improve the identification of patients who might benefit from cancer immunotherapy. We …

Oncogenic lesions up-regulate bioenergetically demanding cellular processes, such as protein
synthesis, to drive cancer cell growth and continued proliferation. However, the hijacking …

Tb 2 O 3 coated with a polysiloxane layer is a biocompatible nanoscintillator that exhibits an
appropriate pattern of biodistribution after injection. In this contribution, we combine this …

AGuIX nanoparticles are formed of a polysiloxane network surrounded by gadolinium chelates.
They present several characteristics. They are easy to produce, they present very small …

While there have been tremendous efforts to target oncogenic RAS signaling from inside
the cell, little effort has focused on the cell-surface. Here, we used quantitative surface …

There is limited knowledge about the metabolic reprogramming induced by cancer therapies
and how this contributes to therapeutic resistance. Here we show that although inhibition of …