User profiles for Charleston Chiang
 | Charleston Wen-Kai ChiangAssociate Professor at University of Southern California Verified email at med.usc.edu Cited by 5469 |
[HTML][HTML] Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies
…, E Frackelton, N Patterson, CWK Chiang… - PloS one, 2008 - journals.plos.org
A wealth of genetic associations for cardiovascular and metabolic phenotypes in humans
has been accumulating over the last decade, in particular a large number of loci derived from …
has been accumulating over the last decade, in particular a large number of loci derived from …
[HTML][HTML] The influence of age and sex on genetic associations with adult body size and shape: a large-scale genome-wide interaction study
…, G Boucher, G Cadby, YC Cheng, CWK Chiang… - PLoS …, 2015 - journals.plos.org
Genome-wide association studies (GWAS) have identified more than 100 genetic variants
contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHR …
contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHR …
Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European
Ancient genomic sequences have started to reveal the origin and the demographic impact
of farmers from the Neolithic period spreading into Europe 1 , 2 , 3 . The adoption of farming, …
of farmers from the Neolithic period spreading into Europe 1 , 2 , 3 . The adoption of farming, …
[PDF][PDF] Direct regulation of adult brain function by the male-specific factor SRY
P Dewing, CWK Chiang, K Sinchak, H Sim… - Current Biology, 2006 - cell.com
The central dogma of mammalian brain sexual differentiation has contended that sex steroids
of gonadal origin organize the neural circuits of the developing brain [1]. Recent evidence …
of gonadal origin organize the neural circuits of the developing brain [1]. Recent evidence …
[PDF][PDF] Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations
Most loci identified by GWASs have been found in populations of European ancestry (EUR).
In trans-ethnic meta-analyses for 15 hematological traits in 746,667 participants, including …
In trans-ethnic meta-analyses for 15 hematological traits in 746,667 participants, including …
Evidence of widespread selection on standing variation in Europe at height-associated SNPs
MC Turchin, CWK Chiang, CD Palmer… - Nature …, 2012 - nature.com
Strong signatures of positive selection at newly arising genetic variants are well documented
in humans 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , but this form of selection may not be widespread in …
in humans 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , but this form of selection may not be widespread in …
Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies
10.7554/eLife.39702.001 Genetic predictions of height differ among human populations
and these differences have been interpreted as evidence of polygenic adaptation. These …
and these differences have been interpreted as evidence of polygenic adaptation. These …
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry
Genome-wide association studies (GWAS) have identified 36 loci associated with body mass
index (BMI), predominantly in populations of European ancestry. We conducted a meta-…
index (BMI), predominantly in populations of European ancestry. We conducted a meta-…
Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers
…, A Kwong, VD Ortega del Vecchyo, CWK Chiang… - Nature …, 2015 - nature.com
We report ∼17.6 million genetic variants from whole-genome sequencing of 2,120 Sardinians;
22% are absent from previous sequencing-based compilations and are enriched for …
22% are absent from previous sequencing-based compilations and are enriched for …
Population structure of Han Chinese in the modern Taiwanese population based on 10,000 participants in the Taiwan Biobank project
CH Chen, JH Yang, CWK Chiang… - Human molecular …, 2016 - academic.oup.com
The Taiwan Biobank (TWB) aims to build a nationwide research database that integrates
genomic/epigenomic profiles, lifestyle patterns, dietary habits, environmental exposure history …
genomic/epigenomic profiles, lifestyle patterns, dietary habits, environmental exposure history …