Pichia pastoris is an important host for recombinant protein production. As a protein production
platform, further development for therapeutic glycoproteins has been hindered by the high…

Yeasts are valuable hosts for recombinant protein production, as these unicellular eukaryotes
are easy to handle, grow rapidly to a high cell density on cost-effective defined media, …

The glycosylation pathways of several eukaryotic protein expression hosts are being
engineered to enable the production of therapeutic glycoproteins with humanized application‐…

… Charlot De Wachter performed the native mannoyslation analysis. Bram Laukens, Riet
De Rycke and Michiel De Bruyne carried out the TEM work. David Bell carried out the mass …

Background Cystic fibrosis transmembrane conductance regulator (CFTR) modulators correct
the basic defect caused by CFTR mutations. Improvements in health outcomes have been …

Within bacterial populations, a small fraction of persister cells is transiently capable of surviving
exposure to lethal doses of antibiotics. As a bet-hedging strategy, persistence levels are …

Deep mutational scanning is a powerful approach to investigate a wide variety of research
questions including protein function and stability. Here, we perform deep mutational scanning …

Antibiotic resistance in the important opportunistic human pathogen Streptococcus
pneumoniae is on the rise. This is particularly problematic in the case of the β-lactam antibiotic …

… Author Charlot De Wachter (UGent) … De Wachter C. Exploring the influence of N-glycosylation
on allergen-specific immunotherapy. [Ghent, Belgium]: Ghent University. … De Wachter, “Exploring …

… Stefan De Wachter receives paid consulting fees from Medtronic as honoraria for invited
speaker. Paul Lehur has consulting agreements with Medtronic and B.Braun… Stefan De Wachter …