A deficient interferon (IFN) response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection has been implicated as a determinant of severe coronavirus disease …

The HIV-1 Nef protein suppresses multiple immune surveillance mechanisms to promote
viral pathogenesis and is an attractive target for the development of novel therapeutics. A key …

Two flavonol tetraglycosides comprising a trisaccharide at C-3 and a monosaccharide at C-7
were isolated from the leaves of Styphnolobium japonicum (L.) Schott and characterised as …

SARS-CoV-2 is the novel coronavirus that is the causative agent of COVID-19, a sometimes-lethal
respiratory infection responsible for a world-wide pandemic. The envelope (E) protein, …

Adeno-associated virus/phage (AAVP) is a gene delivery vector constructed as a hybrid
between adeno-associated virus and filamentous phage. Tumor targeting following systemic …

Bacteriophage (phage) have attractive advantages as delivery systems compared with
mammalian viruses, but have been considered poor vectors because they lack evolved strategies …

The plasma membrane is a site of conflict between host defenses and many viruses. One
aspect of this conflict is the host’s attempt to eliminate infected cells using innate and adaptive …

Legionella pneumophila is an intracellular bacterium that resides within amoebae and
macrophages in a specialized compartment termed the Legionella -containing vacuole (LCV). As …

Suicide gene transfer is the most commonly used cytotoxic approach in cancer gene therapy;
however, a successful suicide gene therapy depends on the generation of efficient …

Legionella pneumophila , the causative agent of Legionnaires’ disease, uses the Dot/Icm
type IV secretion system (T4SS) to translocate more than 300 effectors into host cells, where …