User profiles for Chathurika Henpita

Chathurika Henpita

Postdoctoral Associate
Verified email at okstate.edu
Cited by 408

[HTML][HTML] DNA damage—how and why we age?

M Yousefzadeh, C Henpita, R Vyas, C Soto-Palma… - Elife, 2021 - elifesciences.org
Aging is a complex process that results in loss of the ability to reattain homeostasis following
stress, leading, thereby, to increased risk of morbidity and mortality. Many factors contribute …

Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments

R Greenway, N Barts, C Henpita… - Proceedings of the …, 2020 - National Acad Sciences
Extreme environments test the limits of life; yet, some organisms thrive in harsh conditions.
Extremophile lineages inspire questions about how organisms can tolerate physiochemical …

The roles of plasticity and evolutionary change in shaping gene expression variation in natural populations of extremophile fish

CN Passow, C Henpita, JH Shaw… - Molecular …, 2017 - Wiley Online Library
The notorious plasticity of gene expression responses and the complexity of environmental
gradients complicate the identification of adaptive differences in gene regulation among …

Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy

C Henpita, R Vyas, CL Healy, TL Kieu, AU Gurkar… - Aging cell, 2023 - Wiley Online Library
Cardiomyopathy is a progressive disease of the myocardium leading to impaired contractility.
Genotoxic cancer therapies are known to be potent drivers of cardiomyopathy, whereas …

H2S exposure elicits differential expression of candidate genes in fish adapted to sulfidic and non-sulfidic environments

M Tobler, C Henpita, B Bassett, JL Kelley… - … and Physiology Part A …, 2014 - Elsevier
Disentangling the effects of plasticity, genetic variation, and their interactions on organismal
responses to environmental stressors is a key objective in ecological physiology. We …

[HTML][HTML] Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association

…, A Kumar, CL Green, C Soto-Palma, C Henpita… - Geroscience, 2021 - Springer
Chathurika HenpitaChathurika Henpita presented evidence that a decline in
mitochondrial homeostasis contributes to cellular senescence, and that mitochondrial targeted …

Metabolic rate as a function of ambient temperature in crickets, cockroaches and mice

…, C Desilva, J May, CR Henpita - Journal of …, 2015 - undergradsciencejournals.okstate …
The topic of this paper examines how temperature influences metabolic rate. The key
question under examination is why do animals eat differently under different environmental …

Erratum:“Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments,”(Proceedings of the National Academy …

R Greenway, N Barts, C Henpita… - Proceedings of the …, 2020 - experts.umn.edu
The authors note that, due to a printer’s error, the author line appeared incorrectly. The authors
Michael Tobler, Joanna L. Kelley, and Jennifer H. Shaw should appear in the author line …

H2S‐tolerant Fish Differentially Express Genes and Modify Mitochondrial Function to Maintain H2S Homeostasis

J Shaw, C Henpita, M Tobler - The FASEB Journal, 2015 - Wiley Online Library
Hydrogen sulfide (H 2 S) is a toxic gas that inhibits the final step in the mitochondrial electron
transport chain. This gas, however, is produced endogenously at low levels to promote …

What's in the Water: Why Lakes exhibit decreased dissolved oxygen concentrations due to Eutrophication.

K Dixon, C Ayisi, C Henpita - Journal of …, 2015 - undergradsciencejournals.okstate …
Eutrophication can be best described as the enrichment of an ecosystem with chemical
nutrients, typically compounds containing nitrogen, phosphorus, or both (Correll 1995). When …