The molecular composition and binding epitopes of the immunoglobulin G (IgG) antibodies
that circulate in blood plasma after severe acute respiratory syndrome coronavirus 2 (SARS-…

γ-Secretase is a multisubunit complex that catalyzes intramembranous cleavage of transmembrane
proteins. The lipid environment forms membrane microdomains that serve as spatio-…

Affinity probes are useful tools for determining molecular targets and elucidating mechanism
of action for novel, bioactive compounds. In the case of covalent inhibitors, activity based …

Although humoral immunity is essential for control of SARS-CoV-2, the molecular composition,
binding epitopes and effector functions of the immunoglobulin G (IgG) antibodies that …

The global battle against the Covid-19 pandemic relies strongly on the human defence of
antibody, which is assumed to bind the Receptor Binding Domain of the antigen with its …

Here we describe YESS 2.0, a highly versatile version of the yeast endoplasmic
sequestration screening (YESS) system suitable for engineering and characterizing protein/peptide …

Due to the emerging importance of the bromodomain binding region in the study of epigenetic
effectors and the vast implications for a wide variety of human disease, the bromodomain …

We used plasma IgG proteomics to study the molecular composition and temporal durability
of polyclonal IgG antibodies triggered by ancestral SARS-CoV-2 infection, vaccination, or …

… Chelsea Paresi was born in Salt Lake City, Utah in 1988. … Chelsea has always had a
strong interest in pharmacological … Chelsea was an active member in the graduate school …

Extensive efforts have been made to study the human immune response following SARS-CoV-2
infection. Recent work by our lab provided insights into the molecular-level composition …