User profiles for Chengjin Ye

Chengjin Ye

Texas Biomedical Research Institute
Verified email at txbiomed.org
Cited by 2339

Multi-objective optimal power flow considering transient stability based on parallel NSGA-II

CJ Ye, MX Huang - IEEE Transactions on Power Systems, 2014 - ieeexplore.ieee.org
Stability is an important constraint in power system operation and the transient stability
constrained optimal power flow (OPF) has always received considerable attention in recent years. …

[HTML][HTML] SARS-CoV-2 spike E484K mutation reduces antibody neutralisation

S Jangra, C Ye, R Rathnasinghe, D Stadlbauer… - The Lancet …, 2021 - thelancet.com
It is concerning that emerging variants of SARS-CoV-2 can evade neutralising antibodies
induced by previous infection or vaccination through mutations in the spike protein, including …

Rescue of SARS-CoV-2 from a single bacterial artificial chromosome

C Ye, K Chiem, JG Park, F Oladunni, RN Platt… - MBio, 2020 - Am Soc Microbiol
Infectious coronavirus (CoV) disease 2019 (COVID-19) emerged in the city of Wuhan (China)
in December 2019, causing a pandemic that has dramatically impacted public health and …

[HTML][HTML] Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice

…, S Gautam, A Garcia-Vilanova, C Ye… - Nature …, 2020 - nature.com
Vaccine and antiviral development against SARS-CoV-2 infection or COVID-19 disease
would benefit from validated small animal models. Here, we show that transgenic mice …

[HTML][HTML] Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera

R Rathnasinghe, S Jangra, C Ye, A Cupic… - Nature …, 2022 - nature.com
Due to differences in human and murine angiotensin converting enzyme 2 (ACE-2) receptor,
initially available SARS-CoV-2 isolates could not infect mice. Here we show that serial …

Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors

…, AM Khalil, C Nnabuife, FL Kearns, C Ye… - Science …, 2023 - science.org
Vaccines and drugs have helped reduce disease severity and blunt the spread of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). However, ongoing virus transmission…

SARS-CoV-2 3CLpro mutations selected in a VSV-based system confer resistance to nirmatrelvir, ensitrelvir, and GC376

…, F Costacurta, SA Moghadasi, C Ye… - Science translational …, 2022 - science.org
Protease inhibitors are among the most powerful antiviral drugs. Nirmatrelvir is the first
protease inhibitor specifically developed against the SARS-CoV-2 protease 3CL pro that has …

Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses

C Ye, K Chiem, JG Park, JA Silvas… - Proceedings of the …, 2021 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the
current COVID-19 pandemic, is one of the biggest threats to public health. However, the …

[PDF][PDF] SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming

…, MG Knight, RE Turn, LS Rojas-Hernandez, C Ye… - Cell, 2023 - cell.com
How SARS-CoV-2 penetrates the airway barrier of mucus and periciliary mucins to infect
nasal epithelium remains unclear. Using primary nasal epithelial organoid cultures, we found …

Generation and Characterization of recombinant SARS-CoV-2 expressing reporter genes

…, T Anderson, MR Walter, JJ Kobie, C Ye… - Journal of …, 2021 - Am Soc Microbiol
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
pathogen responsible for coronavirus disease 2019 (COVID-19), has devastated public health …