User profiles for Chengran Yang

Chengran Yang

- Verified email at wustl.edu - Cited by 579

Yang Chengran

- Verified email at smu.edu.sg - Cited by 96

Chengran Yang

- Verified email at nus.edu.sg - Cited by 80

Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders

C Yang, FHG Farias, L Ibanez, A Suhy, B Sadler… - Nature …, 2021 - nature.com
Understanding the tissue-specific genetic controls of protein levels is essential to uncover
mechanisms of post-transcriptional gene regulation. In this study, we generated a genomic …

Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease

YJ Sung, C Yang, J Norton, M Johnson… - Science translational …, 2023 - science.org
Proteomic studies for Alzheimer’s disease (AD) are instrumental in identifying AD pathways
but often focus on single tissues and sporadic AD cases. Here, we present a proteomic study …

MicroRNA profiling reveals marker of motor neuron disease in ALS models

…, AJ Wegener, TS Hyman, C Yang… - Journal of …, 2017 - Soc Neuroscience
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder marked by
the loss of motor neurons (MNs) in the brain and spinal cord, leading to fatally debilitating …

Ptm4tag: sharpening tag recommendation of stack overflow posts with pre-trained models

J He, B Xu, Z Yang, DG Han, C Yang, D Lo - Proceedings of the 30th …, 2022 - dl.acm.org
Stack Overflow is often viewed as one of the most influential Software Question & Answer (SQA)
websites, containing millions of programming-related questions and answers. Tags play …

[HTML][HTML] Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes

C Yang, AM Fagan, RJ Perrin, H Rhinn, O Harari… - Genome medicine, 2022 - Springer
Background Human proteins are widely used as drug targets. Integration of large-scale
protein-level genome-wide association studies (GWAS) and disease-related GWAS has thus …

[PDF][PDF] Cell-type-specific profiling of alternative translation identifies regulated protein isoform variation in the mouse brain

D Sapkota, AM Lake, W Yang, C Yang, H Wesseling… - Cell reports, 2019 - cell.com
Alternative translation initiation and stop codon readthrough in a few well-studied cases have
been shown to allow the same transcript to generate multiple protein variants. Because the …

Aspect-based api review classification: How far can pre-trained transformer model go?

C Yang, B Xu, JY Khan, G Uddin, D Han… - … on Software Analysis …, 2022 - ieeexplore.ieee.org
APIs (Application Programming Interfaces) are reusable software libraries and are building
blocks for modern rapid software development. Previous research shows that programmers …

The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion

…, F Wang, AM Lake, Y Deming, J Perez, C Yang… - Acta …, 2020 - Springer
Apart from amyloid β deposition and tau neurofibrillary tangles, Alzheimer's disease (AD) is
a neurodegenerative disorder characterized by neuronal loss and astrocytosis in the …

Provably superior accuracy in quantum stochastic modeling

C Yang, AJP Garner, F Liu, N Tischler, J Thompson… - Physical Review A, 2023 - APS
In the design of stochastic models, there is a constant trade-off between model complexity
and accuracy. Here we prove that quantum models enable a more favorable trade-off. We …

Post2vec: Learning distributed representations of Stack Overflow posts

B Xu, T Hoang, A Sharma, C Yang… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
Past studies have proposed solutions that analyze Stack Overflow content to help users find
desired information or aid various downstream software engineering tasks. A common step …