Background Mutation of a single amino acid residue can cause changes in a protein, which
could then lead to a loss of protein function. Predicting the protein stability changes can …

Visual communication over wireless channels is becoming important in multimedia. Because
of the limited bandwidth and high error rates of the wireless channel, the video codec …

The aim of this study was to investigate the expression of interleukin-20 (IL-20) and its
receptors on psoriatic skin by immunohistochemical analysis and to evaluate the correlation of …

Protein mutations can lead to structural changes that affect protein function and result in
disease occurrence. In protein engineering, drug design or and optimization industries, …

To develop the enterovirus 71 (EV71) vaccine, we previously constructed a recombinant
baculovirus (Bac-P1-3CD) co-expressing EV71 P1 (under polyhedrin promoter) and 3CD (…

IL-20 belongs to the IL-10 family and plays a role in skin inflammation and the development
of hematopoietic cells. Little is known about its other biological functions and clinical …

The acquisition of resistance is a major obstacle to the clinical use of platinum drugs for
ovarian cancer treatment. Increase of DNA damage response is one of major mechanisms …

Oncogene-induced senescence (OIS) is a stable cell cycle arrest that occurs in normal cells
upon oncogene activation. Cells undergoing OIS express a wide variety of secreted factors …

A series of bis(hydroxymethyl)indolizino[6,7-b]indoles and their bis(alkylcarbamates) were
synthesized for antitumor studies. These agents were designed as hybrid molecules of β-…

Genetically modified plants and crops can contribute to remarkable increase in global food
supply, with improved yield and resistance to plant diseases or insect pests. The …