Tissue engineering is a rapidly evolving discipline that seeks to repair, replace, or regenerate
specific tissues or organs by translating fundamental knowledge in physics, chemistry, and …

Disrupted-in-Schizophrenia-1 (DISC1), identified by positional cloning of a balanced translocation
(1;11) with the breakpoint in intron 8 of a large Scottish pedigree, is associated with a …

Stem cell activation and development is central to skeletal development, maintenance, and
repair, as it is for all tissues. However, an integrated model of stem cell proliferation, …

Background: The rational design and optimization of tissue engineering strategies for cell-based
therapy requires a baseline understanding of the concentration and prevalence of …

We have generated a series of stably transfected HEK-293 cell lines expressing the newly
identified alternate human PTH receptor (hPTH2 receptor). This receptor subtype is …

Nel (neural epidermal growth factor (EGF)-like molecule) is a multimeric, multimodular
extracellular glycoprotein with heparin-binding activity and structural similarities to …

Parathyroid hormone (PTH) and PTH-related protein (PTHrP) are calciotropic hormones
interacting with a shared seven-transmembrane domain G protein-coupled receptor, which is …

The PTH and PTH-related protein (PTHrP) system consists of two hormones, at least two G
protein-coupled seven-transmembrane domain receptors, and at least two intracellular signal …

Embryonic stem cells (ESCs) promise an unlimited source of defined cells for cell transplantation
therapy, while protocols for derivation of homogeneous populations of desirable cell …

It is well established that intermittently administered human parathyroid hormone, hPTH(1–84),
and its fragment hPTH(1–34) effectively increase bone mass in animals and humans. …