Preventing SARS-CoV-2 infection by modulating viral host receptors, such as angiotensin-converting
enzyme 2 (ACE2) 1 , could represent a new chemoprophylactic approach for …

COVID-19 is a spectrum of clinical symptoms in humans caused by infection with SARS-CoV-2.
The B.1.1.529 Omicron variant is rapidly emerging and has been designated a Variant of …

The successful development of a chemoprophylaxis against SARS-CoV-2 could provide a
tool for infection prevention that is implementable alongside vaccination programmes. …

Pibrentasvir (PIB) has been demonstrated to block exonuclease activity of the SARS-CoV-2
polymerase, protecting favipiravir (FVP) and remdesivir (RDV) from post-incorporation …

Objectives: Immunocompromised individuals are susceptible to severe COVID-19 and
potentially contribute to the emergence of variants with altered pathogenicity due to persistent …

BACKGROUND • Sotrovimab (SOT) demonstrates molar potency against previous SARS-CoV-2
variants, reducing the risk of hospitalization and death in patients at high risk of …

Myosin heavy chain 9 (MYH9) was documented as an essential factor for herpesvirus infection.
However, the detailed domain of MYH9 being involved in herpesvirus infection and as a …

… Rebekah Penrice-Randal; Eleanor G Bentley; Parul Sharma; Adam Kirby; I'ah Donovan-Banfield;
Anja Kipar; Daniele F Mega; Chloe Bramwell; Joanne Sharp; Andrew Owen; Julian A Hiscox; …

Background Achieving hepatitis C elimination requires novel approaches to engage people
at highest risk of infection into care pathways. Point-of-care-tests may help to overcome …

Cities everywhere are struggling to develop strategic responses to vast and rapid economic
changes brought about by globalization while mediating the social impact of economic …