… effectively blocked by g-DGG. We found that the effect of g-DGG was enhanced even after
only two iterations of HFSs (Figure 5C). In slices pretreated with MSO, the effect of g-DGG was …

In addition to affecting respiration and vascular tone, deviations from normal CO 2 alter pH,
consciousness, and seizure propensity. Outside the brainstem, however, the mechanisms by …

Traumatic brain injury (TBI) is a major risk factor for developing pharmaco-resistant epilepsy.
Although disruptions in brain circuitry are associated with TBI, the precise mechanisms by …

Astrocytes are glial cells that interact with neuronal synapses via their distal processes,
where they remove glutamate and potassium (K + ) from the extracellular space following …

Excitatory amino acid transporters (EAATs) are abundantly expressed by astrocytes, rapidly
remove glutamate from the extracellular environment, and restrict the temporal and spatial …

Brain-derived neurotrophic factor (BDNF) is essential for maintaining energy and glucose
balance within the central nervous system. Because the study of its metabolic actions has …

Developing cortical GABAergic interneurons rely on genetic programs, neuronal activity,
and environmental cues to construct inhibitory circuits during early postnatal development. …

Genetically encoded fluorescent glutamate indicators (iGluSnFRs) enable neurotransmitter
release and diffusion to be visualized in intact tissue. Synaptic iGluSnFR signal time courses …

Glutamate uptake by astrocytes controls the time course of glutamate in the extracellular
space and affects neurotransmission, synaptogenesis, and circuit development. Astrocytic …

Traumatic brain injury (TBI) is defined as an alteration in brain function or other evidence of
brain pathology caused by an external force. When epilepsy develops following TBI, it is …