Spindle orientation during asymmetric cell division
Abstract Development of a multicellular organism from a fertilized egg depends on a precise
balance between symmetric cell divisions to expand the pool of similar cells, and …
balance between symmetric cell divisions to expand the pool of similar cells, and …
Tools for neuroanatomy and neurogenetics in Drosophila
…, R Svirskas, JT Kadonaga, CQ Doe… - Proceedings of the …, 2008 - National Acad Sciences
We demonstrate the feasibility of generating thousands of transgenic Drosophila melanogaster
lines in which the expression of an exogenous gene is reproducibly directed to distinct …
lines in which the expression of an exogenous gene is reproducibly directed to distinct …
[HTML][HTML] Drosophila neuroblasts sequentially express transcription factors which specify the temporal identity of their neuronal progeny
Neural precursors often generate distinct cell types in a specific order, but the intrinsic or
extrinsic cues regulating the timing of cell fate specification are poorly understood. Here we …
extrinsic cues regulating the timing of cell fate specification are poorly understood. Here we …
The Embryonic Central Nervous System Lineages ofDrosophila melanogaster: I. Neuroblast Lineages Derived from the Ventral Half of the Neuroectoderm
Central nervous system development inDrosophilastarts with the delamination from the
neuroectoderm of about 30 neuroblasts (NBs) per hemisegment. Understanding the …
neuroectoderm of about 30 neuroblasts (NBs) per hemisegment. Understanding the …
The prospero gene specifies cell fates in the Drosophila central nervous system
CQ Doe, Q Chu-LaGraff, DM Wright, MP Scott - Cell, 1991 - cell.com
The molecular mechanisms used to generate neuronal diversity are largely unknown. To
identify genes controlling cell fate in the Drosophila central nervous system, we screened for …
identify genes controlling cell fate in the Drosophila central nervous system, we screened for …
[PDF][PDF] Numb antagonizes Notch signaling to specify sibling neuron cell fates
Asymmetric cell divisions play a key role in establishing neuronal diversity in the mammalian
and Drosophila CNS, but the mechanisms involved are mostly unknown. The Drosophila …
and Drosophila CNS, but the mechanisms involved are mostly unknown. The Drosophila …
Identification of Drosophila type II neuroblast lineages containing transit amplifying ganglion mother cells
Mammalian neural stem cells generate transit amplifying progenitors that expand the
neuronal population, but these type of progenitors have not been studied in Drosophila. The …
neuronal population, but these type of progenitors have not been studied in Drosophila. The …
Clonal analysis of Drosophila embryonic neuroblasts: neural cell types, axon projections and muscle targets
A Schmid, A Chiba, CQ Doe - Development, 1999 - journals.biologists.com
An experimental analysis of neurogenesis requires a detailed understanding of wild-type
neural development. Recent DiI cell lineage studies have begun to elucidate the family of …
neural development. Recent DiI cell lineage studies have begun to elucidate the family of …
Molecular markers for identified neuroblasts and ganglion mother cells in the Drosophila central nervous system
CQ Doe - Development, 1992 - journals.biologists.com
The first step in generating cellular diversity in the Drosophila central nervous system is the
formation of a segmentally reiterated array of neural precursor cells, called neuroblasts. …
formation of a segmentally reiterated array of neural precursor cells, called neuroblasts. …
Neural stem cells: balancing self-renewal with differentiation
CQ Doe - 2008 - journals.biologists.com
Stem cells are captivating because they have the potential to make multiple cell types yet
maintain their undifferentiated state. Recent studies of Drosophila and mammalian neural stem …
maintain their undifferentiated state. Recent studies of Drosophila and mammalian neural stem …