Background Alignment-free (AF) sequence comparison is attracting persistent interest driven
by data-intensive applications. Hence, many AF procedures have been proposed in recent …

Motivation: Alignment-free methods for sequence comparison are increasingly used for genome
analysis and phylogeny reconstruction; they circumvent various difficulties of traditional …

Motivation: Alignment-based methods for sequence analysis have various limitations if large
datasets are to be analysed. Therefore, alignment-free approaches have become popular …

In this article, we present a user-friendly web interface for two alignment-free sequence-comparison
methods that we recently developed. Most alignment-free methods rely on exact …

Motivation Word-based or ‘alignment-free’ algorithms are increasingly used for phylogeny
reconstruction and genome comparison, since they are much faster than traditional …

Alignment-free methods are increasingly used to calculate evolutionary distances between
DNA and protein sequences as a basis of phylogeny reconstruction. Most of these methods, …

Many algorithms for sequence analysis rely on word matching or word statistics. Often, these
approaches can be improved if binary patterns representing match and don’t-care positions …

Word-based or ‘alignment-free’ sequence comparison has become an active research area
in bioinformatics. While previous word-frequency approaches calculated rough measures of …

Background In many fields of biomedical research, it is important to estimate phylogenetic
distances between taxa based on low-coverage sequencing reads. Major applications are, for …

Word-based or ‘alignment-free’ methods for phylogeny inference have become popular in
recent years. These methods are much faster than traditional, alignment-based approaches, …