[HTML][HTML] Body weight selection affects quantitative genetic correlated responses in gut microbiota

H Meng, Y Zhang, L Zhao, W Zhao, C He, CF Honaker… - PloS one, 2014 - journals.plos.org
The abundance of gut microbiota can be viewed as a quantitative trait, which is affected by
the genetics and environment of the host. To quantify the effects of host genetics, we …

[HTML][HTML] Standing genetic variation as a major contributor to adaptation in the Virginia chicken lines selection experiment

Z Sheng, ME Pettersson, CF Honaker, PB Siegel… - Genome biology, 2015 - Springer
Background Artificial selection provides a powerful approach to study the genetics of adaptation.
Using selective-sweep mapping, it is possible to identify genomic regions where allele-…

[HTML][HTML] Gut microbiota co-microevolution with selection for host humoral immunity

…, S Liu, J Ding, R Dai, C He, K Xu, CF Honaker… - Frontiers in …, 2017 - frontiersin.org
To explore coevolution between the gut microbiota and the humoral immune system of the
host, we used chickens as the model organism. The host populations were two lines (HAS …

Sex‐linked barring in chickens is controlled by the CDKN2A /B tumour suppressor locus

…, M Tixier‐Boichard, CF Honaker… - Pigment cell & …, 2010 - Wiley Online Library
… Photos A, B and C supplied by Christa F. Honaker and photo D by Jorma Luhta/naturepl.…
The analysis was performed using 675 F 2 chickens in a three-generation intercross between …

Artificial selection response due to polygenic adaptation from a multilocus, multiallelic genetic architecture

…, M Lillie, L Rönnegård, CF Honaker… - Molecular biology …, 2017 - academic.oup.com
The ability of a population to adapt to changes in their living conditions, whether in nature or
captivity, often depends on polymorphisms in multiple genes across the genome. In-depth …

[HTML][HTML] Genotyping by low-coverage whole-genome sequencing in intercross pedigrees from outbred founders: a cost-efficient approach

Y Zan, T Payen, M Lillie, CF Honaker, PB Siegel… - Genetics Selection …, 2019 - Springer
Background Experimental intercrosses between outbred founder populations are powerful
resources for mapping loci that contribute to complex traits ie quantitative trait loci (QTL). Here…

Intestinal microbiota and host cooperate for adaptation as a hologenome

…, L Xiao, Y Zheng, C Han, FT Akinyemi, CF Honaker… - Msystems, 2022 - Am Soc Microbiol
Multiomic analyses reported here involved two lines of chickens, from a common founder
population, that had undergone long-term selection for high (HWS) or low (LWS) 56-day body …

North American house sparrows are competent for usutu virus transmission

…, J Marano, SA Hawks, E Loessberg, CF Honaker… - Msphere, 2022 - Am Soc Microbiol
Usutu virus (USUV, Flaviviridae) is an emerging mosquito-borne virus that has been
implicated in neuroinvasive disease in humans and epizootic deaths in wild birds. USUV is …

Pathogenesis and shedding of Usutu virus in juvenile chickens

…, J Golden, A Vázquez, CF Honaker… - Emerging Microbes & …, 2021 - Taylor & Francis
Usutu virus (USUV; family: Flaviviridae, genus: Flavivirus), is an emerging zoonotic arbovirus
that causes severe neuroinvasive disease in humans and has been implicated in the loss …

[HTML][HTML] Genome-wide standing variation facilitates long-term response to bidirectional selection for antibody response in chickens

M Lillie, Z Sheng, CF Honaker, BJ Dorshorst… - BMC genomics, 2017 - Springer
Background Long-term selection experiments provide a powerful approach to gain empirical
insights into adaptation, allowing researchers to uncover the targets of selection and infer …