[HTML][HTML] An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

…, GLA Harrison, L Hart, C Henrichs… - Wellcome Open …, 2021 - ncbi.nlm.nih.gov
A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

Genome variation and population structure among 1142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii

…, M Kamali, V Simpson, C Henrichs… - Genome …, 2020 - genome.cshlp.org
Mosquito control remains a central pillar of efforts to reduce malaria burden in sub-Saharan
Africa. However, insecticide resistance is entrenched in malaria vector populations, and …

Genomic epidemiology of artemisinin resistant malaria

…, R Giacomantonio, D Muddyman, C Henrichs… - Elife, 2016 - riip.hal.science
The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is
the result of a soft selective sweep involving at least 20 independent kelch13 mutations. In a …

Genomic epidemiology of the current wave of artemisinin resistant malaria

…, R Giacomantonio, D Muddyman, C Henrichs… - bioRxiv, 2015 - biorxiv.org
Artemisinin resistant Plasmodium falciparum is advancing across Southeast Asia in a soft
selective sweep involving at least 20 independent kelch13 mutations. In a large global survey, …

[PDF][PDF] An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples [version 1; peer review: awaiting

…, WL Hamilton, GLA Harrison21, L Hart, C Henrichs… - researchgate.net
A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

[PDF][PDF] An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples [version 2; peer review

…, WL Hamilton, GLA Harrison21, L Hart, C Henrichs… - academia.edu
A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

Genomic epidemiology of artemisinin resistant malaria

MalariaGEN Plasmodium falciparum Community … - elife, 2016 - elifesciences.org
10.7554/eLife.08714.001 The current epidemic of artemisinin resistant Plasmodium falciparum
in Southeast Asia is the result of a soft selective sweep involving at least 20 independent …

Monitoring parasite diversity for malaria elimination in sub-Saharan Africa

A Ghansah, L Amenga-Etego, A Amambua-Ngwa… - Science, 2014 - science.org
The African continent continues to bear the greatest burden of malaria and the greatest diversity
of parasites, mosquito vectors, and human victims. The evolutionary plasticity of malaria …

[HTML][HTML] Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study

WL Hamilton, R Amato, RW van der Pluijm… - The Lancet Infectious …, 2019 - thelancet.com
Background A multidrug-resistant co-lineage of Plasmodium falciparum malaria, named
KEL1/PLA1, spread across Cambodia in 2008–13, causing high rates of treatment failure with …

[HTML][HTML] Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study

R Amato, RD Pearson, J Almagro-Garcia… - The Lancet Infectious …, 2018 - thelancet.com
Background Antimalarial resistance is rapidly spreading across parts of southeast Asia where
dihydroartemisinin–piperaquine is used as first-line treatment for Plasmodium falciparum …