Cytotoxic T cells are important components of natural anti-tumor immunity and are harnessed
in tumor immunotherapies. Immune responses to tumors and immune therapy outcomes …

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by an
alteration in airway epithelial cell functions including barrier function, wound repair mechanisms, …

Monoclonal antibodies (mAbs) are promising therapies to treat airway chronic inflammatory
disease (asthma or nasal polyps). To date, no study has specifically assessed, in vitro, the …

Bordetella pertussis, the causative agent of whopping cough, produces an adenylate cyclase
toxin (CyaA) that plays a key role in the host colonization by targeting innate immune cells …

T cell-based tumor immunotherapies such as CAR T cells or immune checkpoint inhibitors
harness the cytotoxic potential of T cells to promote tumor regression. However, patient …

Background Information The adenylate cyclase (CyaA) toxin is a major virulent factor of
Bordetella pertussis, the causative agent of whooping cough. CyaA toxin is able to invade …

During total liquid ventilation, lung cells are exposed to perfluorocarbon (PFC) whose
chemophysical properties highly differ from standard aqueous cell feeding medium (DMEM). We …

Background Information Integrin‐mediated adhesion is a key process by which cells
physically connect with their environment, and express sensitivity and adaptation through …

La recrudescence des infections respiratoires impliquant des facteurs virulents d’origine
bactérienne est devenue un problème majeur de santé publique. Mieux caractériser la réponse …

Living cells in the human body are constantly subjected to mechanical stimulation throughout
life. The origin of stresses and strains can arise from both the external environment and …