Alzheimer’s disease (AD) causes the majority of dementia cases worldwide. Early pathological
hallmarks include the accumulation of amyloid-ß (Aß) and activation of both astrocytes …

Hyperdopaminergic states in mental disorders are associated with disruptive deficits in
decision making. However, the precise contribution of topographically distinct mesencephalic …

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive decline,
the neuropathological formation of amyloid-beta (Aβ) plaques and neurofibrillary tangles. …

Alzheimer pathology is accompanied by astrogliosis. Reactive astrocytes surrounding
amyloid plaques may directly affect neuronal communication, and one of the mechanisms by …

Astrocytes are critical for healthy brain function. In Alzheimer’s disease, astrocytes become
reactive, which affects their signaling properties. Here, we measured spontaneous calcium …

Alzheimer's disease (AD) is a progressive neurodegenerative disease and the most
common cause of dementia, characterized by deposition of extracellular amyloid‐beta (Aβ) …

There is increasing evidence of altered tissue mechanics in neurodegeneration. However,
due to difficulties in mechanical testing procedures and the complexity of the brain, there is …

Background: Aging is characterized by systemic alterations and forms an important risk
factor for Alzheimer’s disease (AD). Recently, it has been indicated that blood-borne factors …

Evidence from clinical, preclinical, and post-mortem studies supports the inflammatory/immune
hypothesis of schizophrenia pathogenesis. Less evident is the link between the …

Cover Illustration: Confocal laser scanning microscopy image of astrocytes interacting with
an amyloid-ß plaque in the middle molecular layer of the dentate gyrus in the APPswe/…