Transcription factors provide the link between early membrane-proximal signalling events
and changes in gene expression. NF-kB is one of the best-characterized transcription factors. …

Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 (NT-3)
selectively bind to distinct members of the Trk family of tyrosine kinase receptors, but all …

The transcription factor NF-κB has diverse functions in the nervous system, depending on the
cellular context. NF-κB is constitutively activated in glutamatergic neurons. Knockout of p65 …

We investigated the rat brain for the presence and activation state of the inducible transcription
factor NF-κB. Two forms of NF-κB containing the transactivating p65 subunit were found …

Tissue engineering by stem cell differentiation is a novel treatment option for bone
regeneration. Most approaches for the detection of osteogenic differentiation are invasive or …

Nuclear factor-kappa B (NF-kappaB)/Rel transcription factors play an important role in the
inducible regulation of a variety of genes involved in the inflammatory and proliferative …

Amyloid β peptide (Aβ)-containing plaques are a hallmark of Alzheimer disease. Here, we
show that the neurotoxic Aβ, a major plaque component, is a potent activator of the …

NF-kB is an inducible transcription factor present in many cell types in a latent cytoplasmic
form. So far, only immune cells including mature B cells, thymocytes, and adherent …

Nuclear factor kappa B (NF-κB) is an inducible transcription factor present in neurons and
glia. Recent genetic models identified a role for NF-κB in neuroprotection against various …

To test whether the behaviour of transcription factor NF‐κB as a promoter or antagonist of
apoptosis depends on the apoptotic stimulus, we determined the influence of NF‐κB on cell …