User profiles for Christian Lange
Christian LangeVIB and Katholieke Universiteit Leuven Verified email at vib-kuleuven.be Cited by 1775 |
[PDF][PDF] Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors
C Lange, WB Huttner, F Calegari - Cell stem cell, 2009 - cell.com
During mouse embryonic development, neural progenitors lengthen the G1 phase of the
cell cycle and this has been suggested to be a cause, rather than a consequence, of …
cell cycle and this has been suggested to be a cause, rather than a consequence, of …
[PDF][PDF] Severe lactic acidosis during treatment of chronic hepatitis B with entecavir in patients with impaired liver function
CM Lange, J Bojunga, WP Hofmann, K Wunder… - …, 2009 - Wiley Online Library
Entecavir is a potent nucleoside inhibitor of the hepatitis B virus (HBV) polymerase with a
high antiviral efficacy and a high genetic barrier to viral resistance. After approval in 2006, …
high antiviral efficacy and a high genetic barrier to viral resistance. After approval in 2006, …
[PDF][PDF] Structure at 2.3 Å resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment
C Hunte, J Koepke, C Lange, T Roßmanith, H Michel - Structure, 2000 - cell.com
Background: The cytochrome bc 1 complex is part of the energy conversion machinery of
the respiratory and photosynthetic electron transfer chains. This integral membrane protein …
the respiratory and photosynthetic electron transfer chains. This integral membrane protein …
[HTML][HTML] Specific roles of protein–phospholipid interactions in the yeast cytochrome bc1 complex structure
C Lange, JH Nett, BL Trumpower, C Hunte - The EMBO journal, 2001 - embopress.org
Biochemical data have shown that specific, tightly bound phospholipids are essential for
activity of the cytochrome bc 1 complex (QCR), an integral membrane protein of the respiratory …
activity of the cytochrome bc 1 complex (QCR), an integral membrane protein of the respiratory …
Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c
C Lange, C Hunte - … of the National Academy of Sciences, 2002 - National Acad Sciences
Small diffusible redox proteins facilitate electron transfer in respiration and photosynthesis
by alternately binding to integral membrane proteins. Specific and transient complexes need …
by alternately binding to integral membrane proteins. Specific and transient complexes need …
Paclitaxel-coated balloons reduce restenosis after femoro-popliteal angioplasty: evidence from the randomized PACIFIER trial
…, G Eschenbach, H Hartmann, C Lange… - Circulation …, 2012 - Am Heart Assoc
Background— Peripheral percutaneous transluminal angioplasty is fraught with a substantial
risk of restenosis and reintervention. A drug-eluting balloon (DEB) based on a novel …
risk of restenosis and reintervention. A drug-eluting balloon (DEB) based on a novel …
Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression
…, B Durieux, N Röder, K Löffler, C Lange… - Cancer research, 2008 - AACR
We have previously described a small interfering RNA (siRNA) delivery system (AtuPLEX)
for RNA interference (RNAi) in the vasculature of mice. Here we report preclinical data for …
for RNA interference (RNAi) in the vasculature of mice. Here we report preclinical data for …
A regularized contact model with asymmetric damping and dwell-time dependent friction
Y Gonthier, J McPhee, C Lange… - Multibody System …, 2004 - Springer
A general regularized contact model, including normal compliance, energydissipation, and
tangential friction, is described in this paper. Thenormal damping coefficient is formulated as …
tangential friction, is described in this paper. Thenormal damping coefficient is formulated as …
Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques
…, Z Mankoff, L Wu, M Asokan, C Beil, C Lange… - Science, 2017 - science.org
The development of an effective AIDS vaccine has been challenging because of viral
genetic diversity and the difficulty of generating broadly neutralizing antibodies (bnAbs). We …
genetic diversity and the difficulty of generating broadly neutralizing antibodies (bnAbs). We …
Vascular endothelial growth factor: a neurovascular target in neurological diseases
C Lange, E Storkebaum, CR De Almodóvar… - Nature Reviews …, 2016 - nature.com
Brain function critically relies on blood vessels to supply oxygen and nutrients, to establish a
barrier for neurotoxic substances, and to clear waste products. The archetypal vascular …
barrier for neurotoxic substances, and to clear waste products. The archetypal vascular …