[HTML][HTML] Strength of bacterial adhesion on nanostructured surfaces quantified by substrate morphometry

C Spengler, F Nolle, J Mischo, T Faidt, S Grandthyll… - Nanoscale, 2019 - pubs.rsc.org
Microbial adhesion and the subsequent formation of resilient biofilms at surfaces are
decisively influenced by substrate properties, such as the topography. To date, studies that …

[HTML][HTML] Engineered spider silk-based 2D and 3D materials prevent microbial infestation

S Kumari, G Lang, E DeSimone, C Spengler… - Materials Today, 2020 - Elsevier
Biofilm formation, especially of antimicrobiotic-resistant microbial strains, are a major problem
in health care. Therefore, there is great interest in developing advanced materials that are …

[HTML][HTML] Different binding mechanisms of Staphylococcus aureus to hydrophobic and hydrophilic surfaces

E Maikranz, C Spengler, N Thewes, A Thewes, F Nolle… - Nanoscale, 2020 - pubs.rsc.org
Bacterial adhesion to surfaces is a crucial step in initial biofilm formation. In a combined
experimental and computational approach, we studied the adhesion of the pathogenic …

Candida albicans adhesion to central venous catheters: Impact of blood plasma-driven germ tube formation and pathogen-derived adhesins

P Jung, CE Mischo, G Gunaratnam, C Spengler… - Virulence, 2020 - Taylor & Francis
Candida albicans-related bloodstream infections are often associated with infected central
venous catheters (CVC) triggered by microbial adhesion and biofilm formation. We utilized …

Determination of the nano-scaled contact area of staphylococcal cells

C Spengler, N Thewes, P Jung, M Bischoff, K Jacobs - Nanoscale, 2017 - pubs.rsc.org
Bacterial adhesion is a crucial step during the development of infections as well as the
formation of biofilms. Hence, fundamental research of bacterial adhesion mechanisms is of …

In-depth investigation of copper surface chemistry modification by ultrashort pulsed direct laser interference patterning

…, A Holtsch, S Lößlein, C Pauly, C Spengler… - Langmuir, 2020 - ACS Publications
Surface patterning in the micro- and nanometer-range by means of pulsed laser interference
has repeatedly proven to be a versatile tool for surface functionalization. With these …

[HTML][HTML] Modeling bacterial adhesion to unconditioned abiotic surfaces

C Spengler, E Maikranz, L Santen… - Frontiers in Mechanical …, 2021 - frontiersin.org
Understanding bacterial adhesion as a first step toward biofilm formation is of fundamental
interests in many applications. While adhesion to abiotic surfaces is directly relevant for some …

[HTML][HTML] Human blood plasma factors affect the adhesion kinetics of Staphylococcus aureus to central venous catheters

G Gunaratnam, C Spengler, S Trautmann, P Jung… - Scientific Reports, 2020 - nature.com
Staphylococcus aureus is a common cause of catheter-related blood stream infections (CRBSI).
The bacterium has the ability to form multilayered biofilms on implanted material, which …

Enhanced adhesion of Streptococcus mutans to hydroxyapatite after exposure to saliva

C Spengler, N Thewes, F Nolle, T Faidt… - Journal of Molecular …, 2017 - Wiley Online Library
Streptococcus mutans cells form robust biofilms on human teeth and are strongly related to
caries incidents. Hence, understanding the adhesion of S. mutans in the human oral cavity is …

[HTML][HTML] Data for microbe resistant engineered recombinant spider silk protein based 2D and 3D materials

S Kumari, G Lang, E DeSimone, C Spengler… - Data in Brief, 2020 - Elsevier
Data presented in this article describe bacterial and fungal repellent properties of 2D-films
and 3D-hydrogels made of different recombinantly produced spider silk proteins based on …