User profiles for Christian Vanhove
Christian VanhoveInstitute Biomedical Technology - Medical Imaging and Signal Processing Verified email at UGent.be Cited by 7029 |
Phase I study of 68Ga-HER2-nanobody for PET/CT assessment of HER2 expression in breast carcinoma
…, C Fontaine, I Vaneycken, C Vanhove… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Human epidermal growth factor receptor 2 (HER2) status is one of the major tumor characteristics
in breast cancer to guide therapy. Anti-HER2 treatment has clear survival advantages …
in breast cancer to guide therapy. Anti-HER2 treatment has clear survival advantages …
Comparison of the biodistribution and tumor targeting of two 99mTc-labeled anti-EGFR nanobodies in mice, using pinhole SPECT/micro-CT
Camelidae possess an unusual class of antibodies devoid of light chains. Nanobodies are
intact antigen-binding fragments that are stable, easily generated against different targets, …
intact antigen-binding fragments that are stable, easily generated against different targets, …
Review of SPECT collimator selection, optimization, and fabrication for clinical and preclinical imaging
In single photon emission computed tomography, the choice of the collimator has a major
impact on the sensitivity and resolution of the system. Traditional parallel‐hole and fan‐beam …
impact on the sensitivity and resolution of the system. Traditional parallel‐hole and fan‐beam …
Localization, mechanism and reduction of renal retention of technetium‐99m labeled epidermal growth factor receptor‐specific nanobody in mice
…, V Caveliers, N Devoogdt, C Vanhove… - Contrast media & …, 2011 - Wiley Online Library
Background Nanobodies are single‐domain antigen binding fragments derived from
functional heavy‐chain antibodies elicited in Camelidae. They are powerful probes for …
functional heavy‐chain antibodies elicited in Camelidae. They are powerful probes for …
Cancer-associated adipose tissue promotes breast cancer progression by paracrine oncostatin M and Jak/STAT3 signaling
Increasing evidence supports the critical roles played by adipose tissue in breast cancer
progression. Yet, the mediators and mechanisms are poorly understood. Here, we show that …
progression. Yet, the mediators and mechanisms are poorly understood. Here, we show that …
Radiotherapy-activated cancer-associated fibroblasts promote tumor progression through paracrine IGF1R activation
Preoperative radiotherapy (RT) is a mainstay in the management of rectal cancer, a tumor
characterized by desmoplastic stroma containing cancer-associated fibroblasts (CAF). …
characterized by desmoplastic stroma containing cancer-associated fibroblasts (CAF). …
[HTML][HTML] ESTRO ACROP: Technology for precision small animal radiotherapy research: Optimal use and challenges
Many radiotherapy research centers have recently installed novel research platforms enabling
the investigation of the radiation response of tumors and normal tissues in small animal …
the investigation of the radiation response of tumors and normal tissues in small animal …
Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy: Restoring the immunogenicity of immunosilent mRNA
…, M Van Bockstal, B Descamps, C Vanhove… - Journal of Controlled …, 2017 - Elsevier
This study reports on the design of mRNA and adjuvant-loaded lipid nanoparticles for
therapeutic cancer vaccination. The use of nucleoside-modified mRNA has previously been …
therapeutic cancer vaccination. The use of nucleoside-modified mRNA has previously been …
Sortase A‐mediated site‐specific labeling of camelid single‐domain antibody‐fragments: a versatile strategy for multiple molecular imaging modalities
A generic site‐specific conjugation method that generates a homogeneous product is of
utmost importance in tracer development for molecular imaging and therapy. We explored the …
utmost importance in tracer development for molecular imaging and therapy. We explored the …
Angiopoietin‐2 promotes pathological angiogenesis and is a therapeutic target in murine nonalcoholic fatty liver disease
…, S Neyt, B Vandeghinste, C Vanhove… - …, 2019 - Wiley Online Library
Angiogenesis contributes to the development of nonalcoholic steatohepatitis (NASH) and
promotes inflammation, fibrosis, and progression to hepatocellular carcinoma (HCC). …
promotes inflammation, fibrosis, and progression to hepatocellular carcinoma (HCC). …