Background Recent outbreaks of avian influenza A (H5N1) in poultry throughout Asia have
had major economic and health repercussions. Human infections with this virus were …

Background Antimicrobial resistance (AMR) represents one of the most crucial threats to
public health and modern health care. Previous studies have identified challenges with …

Background . Malaria in humans is caused by apicomplexan parasites belonging to 5 species
of the genus Plasmodium. Infections with Plasmodium ovale are widely distributed but …

Isolates of Salmonella enterica serovar Typhi (Typhi), a human-restricted bacterial
pathogen that causes typhoid, show limited genetic variation. We generated whole-genome …

Background Efforts to quantify the global burden of enteric fever are valuable for understanding
the health lost and the large-scale spatial distribution of the disease. We present the …

We describe an analysis of genome variation in 825 P. falciparum samples from Asia and
Africa that identifies an unusual pattern of parasite population structure at the epicenter of …

The emergence of multidrug-resistant (MDR) typhoid is a major global health threat affecting
many countries where the disease is endemic. Here whole-genome sequence analysis of …

Background Antimicrobial resistance (AMR) is a serious threat to global public health. WHO
emphasises the need for countries to monitor antibiotic consumption to combat AMR. Many …

For microbial pathogens, phylogeographic differentiation seems to be relatively common.
However, the neutral population structure of Salmonella enterica serovar Typhi reflects the …

Background Non-typhoidal salmonella invasive disease is a major cause of global morbidity
and mortality. Malnourished children, those with recent malaria or sickle-cell anaemia, and …