[HTML][HTML] A molecular cell atlas of the human lung from single-cell RNA sequencing
Although single-cell RNA sequencing studies have begun to provide compendia of cell
expression profiles 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 – 9 , it has been difficult to systematically identify and …
expression profiles 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 – 9 , it has been difficult to systematically identify and …
[HTML][HTML] Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris: The Tabula Muris Consortium
We have created a compendium of single cell transcriptomic data from the model organism
Mus musculus comprising more than 100,000 cells from 20 organs and tissues. These data …
Mus musculus comprising more than 100,000 cells from 20 organs and tissues. These data …
[HTML][HTML] Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
Angiotensin-converting enzyme 2 (ACE2) and accessory proteases (TMPRSS2 and CTSL)
are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular entry…
are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular entry…
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral …
The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, creates an urgent
need for identifying molecular mechanisms that mediate viral entry, propagation, and tissue …
need for identifying molecular mechanisms that mediate viral entry, propagation, and tissue …
[HTML][HTML] Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells
The proposed cis-Golgi vesicle receptor syntaxin 5 was found in a complex with Golgi-associated
SNARE of 28 kDa (GOS-28), rbet1, rsly1, and two novel proteins characterized herein: …
SNARE of 28 kDa (GOS-28), rbet1, rsly1, and two novel proteins characterized herein: …
[PDF][PDF] Rare pulmonary neuroendocrine cells are stem cells regulated by Rb, p53, and Notch
…, ER Rojas, DP Riordan, S Capostagno, CS Kuo… - Cell, 2019 - cell.com
Pulmonary neuroendocrine (NE) cells are neurosensory cells sparsely distributed throughout
the bronchial epithelium, many in innervated clusters of 20–30 cells. Following lung injury, …
the bronchial epithelium, many in innervated clusters of 20–30 cells. Following lung injury, …
Localization, dynamics, and protein interactions reveal distinct roles for ER and Golgi SNAREs
…, V Oorschot, M Steegmaier, CS Kuo… - The Journal of cell …, 1998 - rupress.org
ER-to-Golgi transport, and perhaps intraGolgi transport involves a set of interacting soluble
N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) proteins including …
N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) proteins including …
[PDF][PDF] Formation of a neurosensory organ by epithelial cell slithering
CS Kuo, MA Krasnow - Cell, 2015 - cell.com
Epithelial cells are normally stably anchored, maintaining their relative positions and
association with the basement membrane. Developmental rearrangements occur through cell …
association with the basement membrane. Developmental rearrangements occur through cell …
[HTML][HTML] Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer
…, YA Zhang, D Deb, V Stastny, K Pozo, CS Kuo… - Communications …, 2021 - nature.com
Small cell lung cancer (SCLC) is classified as a high-grade neuroendocrine (NE) tumor, but
a subset of SCLC has been termed “variant” due to the loss of NE characteristics. In this …
a subset of SCLC has been termed “variant” due to the loss of NE characteristics. In this …
Neuroendocrinology of the lung revealed by single-cell RNA sequencing
CS Kuo, S Darmanis, AD de Arce, Y Liu, N Almanzar… - Elife, 2022 - elifesciences.org
Pulmonary neuroendocrine cells (PNECs) are sensory epithelial cells that transmit airway
status to the brain via sensory neurons and locally via calcitonin gene-related peptide (CGRP) …
status to the brain via sensory neurons and locally via calcitonin gene-related peptide (CGRP) …