Chromatin-based functional genomic analyses and genomewide association studies (GWASs)
together implicate enhancers as critical elements influencing gene expression and risk …

HIV-1-neutralizing antibodies develop in most HIV-1-infected individuals, although highly
effective antibodies are generally observed only after years of chronic infection. Here, we …

Diabetics frequently suffer from chronic, nonhealing wounds. Although bacterial colonization
and/or infection are generally acknowledged to negatively impact wound healing, the …

Synonymous mutations, which do not alter the protein sequence, have been shown to affect
protein function [Sauna ZE, Kimchi-Sarfaty C (2011) Nat Rev Genet 12(10):683–691]. …

Acinetobacter baumannii is an emerging human pathogen and a significant cause of
nosocomial infections among hospital patients worldwide. The enormous increase in multidrug …

Next-generation sequencing of antibody transcripts from HIV-1–infected individuals with
broadly neutralizing antibodies could provide an efficient means for identifying somatic variants …

Carbapenem-resistant Klebsiella pneumoniae strains are formidable hospital pathogens that
pose a serious threat to patients around the globe due to a rising incidence in health care …

Recent advances in sequencing technology have helped unveil the unexpected complexity
and diversity of small RNAs. A critical step in small RNA library preparation for sequencing is …

Next-generation sequencing of antibody transcripts provides a wealth of data, but the ability
to identify function-specific antibodies solely on the basis of sequence has remained elusive. …

Most expression quantitative trait locus (eQTL) studies to date have been performed in
heterogeneous tissues as opposed to specific cell types. To better understand the cell-type–…