Background Interest in spatial fractionation radiotherapy has exponentially increased over
the last decade as a significant reduction of healthy tissue toxicity was observed by mini‐…

Anti-CRISPR (Acr) proteins are powerful tools to control CRISPR–Cas technologies. However,
the available Acr repertoire is limited to naturally occurring variants. Here, we applied …

Over recent decades, stereotactic body radiotherapy has garnered increasing popularity.
Unfortunately, conventional preclinical 2D in vitro models are often insufficient for studying …

The oral cavity with the teeth and the surrounding gingival epithelium, the periodontium, the
salivary glands and other structures are open to the oral environment and thus exposed to …

Optogenetic control of CRISPR–Cas9 systems has significantly improved our ability to perform
genome perturbations in living cells with high precision in time and space. As new Cas …

Objective. This work investigates the use of Al 2 O 3: C and Al 2 O 3: C, Mg optically stimulated
luminescence (OSL) detectors to determine both the dose and the radiation quality in light …

Objective. Carbon ion radiotherapy is a promising radiation technique for malignancies like
pancreatic cancer. However, organs' motion imposes challenges for achieving …

Purpose. Improvements in image-guided radiotherapy (IGRT) enable accurate and precise
treatment of moving tumors in the abdomen while simultaneously sparing healthy tissue. …

Background: The oral cavity along with the teeth and the surrounding gingival epithelium is
open to the oral environment and is thus exposed to multiple microbiological and pathogenic …

Availability of oxygen plays an important role in tissue organization and cell-type specific
metabolism. It is, however, difficult to analyze hypoxia-related adaptations in vitro because of …