The role of cancer stem cells in tumor heterogeneity and resistance to therapy

CV Konrad, R Murali, BA Varghese… - Canadian Journal of …, 2017 - cdnsciencepub.com
Cancer is a heterogenous disease displaying marked inter- and intra-tumoral diversity. The
existence of cancer stem cells (CSCs) has been experimentally demonstrated in a number of …

[HTML][HTML] Id proteins promote a cancer stem cell phenotype in mouse models of triple negative breast cancer via negative regulation of Robo1

…, AS Cazet, DL Roden, K Harvey, CV Konrad… - Frontiers in Cell and …, 2020 - frontiersin.org
Breast cancers display phenotypic and functional heterogeneity and several lines of
evidence support the existence of cancer stem cells (CSCs) in certain breast cancers, a minor …

[HTML][HTML] Targeting the Id1-Kif11 axis in triple-negative breast cancer using combination therapy

…, A McFarland, DL Roden, H Holliday, CV Konrad… - Biomolecules, 2020 - mdpi.com
The basic helix-loop-helix (bHLH) transcription factors inhibitor of differentiation 1 (Id1) and
inhibitor of differentiation 3 (Id3) (referred to as Id) have an important role in maintaining the …

Id proteins promote a cancer stem cell phenotype in triple negative breast cancer via negative regulation of Robo1

…, AS Cazet, DL Roden, K Harvey, CV Konrad… - bioRxiv, 2018 - biorxiv.org
Background Breast cancers display phenotypic and functional heterogeneity. Several lines
of evidence support the existence of cancer stem cells (CSCs) in certain breast cancers, a …

Targeting the Id1-Kif11-Aurka axis in triple negative breast cancer using combination therapy

…, A McFarland, DL Roden, H Holliday, C Konrad… - bioRxiv, 2019 - biorxiv.org
Evidence points to breast cancer following a hierarchical model, with Cancer Stem Cells (CSCs)
driving critical phenotypes of the bulk tumor. Chemoresistant CSCs are not an abstract …

[HTML][HTML] Comparable human reconstitution following Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice

AHF Andersen, SSF Nielsen, R Olesen, JLF Harslund… - Plos one, 2020 - journals.plos.org
… We also thank Christina Valbirk Konrad, Frederik Holm Rothemejer and Maria Lange
Pedersen for their indispensable assistance with tissue processing. …

Nanobody‐mediated complement activation to kill HIV‐infected cells

ML Pedersen, DV Pedersen, MBL Winkler… - EMBO Molecular …, 2023 - embopress.org
… We would like to thank Emma Falling Iversen and Kathrine Kjær for virus production, Christina
Valbirk Konrad for the generation of scFv10-1074, and Laura Traberg-Nyborg for assisting …

[PDF][PDF] Mental health of people with chronic respiratory failure receiving home mechanical ventilation: a scoping review

ML Pedersen, C Handberg… - PhD Day …, 2021 - findresearchersdu.elsevierpure.com
Methods In this cross-sectional study with one-stage cluster-randomised sampling newly
arrived adult Syrian refugees were included between 2016 and 2019 in refugee camps and …

Pharmacological Inhibition of REST in Glioblastoma

M Haraguchi, C Li, L Kukreja, S Ezhilan… - … REU Abstract Accepted …, 2019 - par.nsf.gov
Introduction: RE1-silencing transcription factor (REST) silences neuronal differentiation
genes. Its overexpression in an aggressive subset of gliomas is believed to support the …

Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1

H Levine, AK Kanugula, E Thompson… - … the Multi-faceted …, 2021 - books.google.com
… Roden 1, 2, Kate Harvey 1, Christina Valbirk Konrad 1, Reshma Murali 3, Binitha Anu
Varghese 3, Archana P. Thankamony3, 4, Chia-Ling Chan 1, 2, Andrea McFarland 1, Simon …