Over 77 million dogs and 93 million cats share our households in the United States. Multiple
studies have demonstrated the importance of pets in their owners' physical and mental …

Cardiac hypertrophy is a common response to injury and hemodynamic stress and an
important harbinger of heart failure and death. Herein, we identify the Kruppel-like factor 15 (…

Control of Leishmania infantum infection is dependent upon Th1 CD4+ T cells to promote
macrophage intracellular clearance of parasites. Deficient CD4+ T cell effector responses …

Mammalian cell invasion by the protozoan parasite, Trypanosoma cruzi, is facilitated by the
activation of host cell phosphatidylinositol 3 (PI 3)-kinases. We demonstrate that the well-…

Background Dogs are the predominant domestic reservoir for human L. infantum infection.
Zoonotic visceral leishmaniasis (ZVL) is an emerging problem in some US dog breeds, with …

In both dogs and humans Leishmania infantum infection is more prevalent than disease, as
infection often does not equate with clinical disease. Previous studies additively indicate that …

Background & Aims Loss of parietal cells causes the development of spasmolytic
polypeptide-expressing metaplasia (SPEM) through transdifferentiation of chief cells. In the presence …

This review discusses leishmaniasis in cats and dogs in the United States. Leishmaniasis is
endemic in Foxhound populations in the United States and is still being characterized in this …

Objective Alternatively activated macrophages (M2) are associated with the progression of
spasmolytic polypeptide-expressing metaplasia (SPEM) in the stomach. However, the precise …

Invasive species are commonly thought to have broad tolerances that enable them to
colonize new habitats, but this assumption has rarely been tested. In particular, the relative …