[HTML][HTML] Ecotoxicoproteomics: A decade of progress in our understanding of anthropogenic impact on the environment

D Gouveia, C Almunia, Y Cogne, O Pible… - Journal of …, 2019 - Elsevier
Anthropogenic pollutants are found worldwide. Their fate and effects on human and
ecosystem health must be appropriately monitored. Today, ecotoxicology is focused on the …

Shotgun proteomics analysis of SARS-CoV-2-infected cells and how it can optimize whole viral particle antigen production for vaccines

…, A Desplan, B Alpha-Bazin, C Almunia… - Emerging Microbes & …, 2020 - Taylor & Francis
Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has resulted in a
pandemic and is continuing to spread rapidly around the globe. No effective vaccine is …

An integrated metabolomics and proteogenomics approach reveals molecular alterations following carbamazepine exposure in the male mussel Mytilus …

T Dumas, F Courant, C Almunia, J Boccard, D Rosain… - Chemosphere, 2022 - Elsevier
Carbamazepine is one of the most abundant pharmaceutical active compounds detected in
aquatic systems. Based on laboratory exposures, carbamazepine has been proven to …

The immune system of the freshwater zebra mussel, Dreissena polymorpha, decrypted by proteogenomics of hemocytes and plasma compartments

M Lepretre, C Almunia, J Armengaud, A Salvador… - Journal of …, 2019 - Elsevier
The immune system of bivalves is of great interest since it reflects the health status of these
organisms during stressful conditions. While immune molecular responses are well …

[HTML][HTML] De novo transcriptomes of 14 gammarid individuals for proteogenomic analysis of seven taxonomic groups

…, O Geffard, J Armengaud, A Chaumot, C Almunia - Scientific Data, 2019 - nature.com
Gammarids are amphipods found worldwide distributed in fresh and marine waters. They
play an important role in aquatic ecosystems and are well established sentinel species in …

Ecotoxico-proteomics for aquatic environmental monitoring: First in situ application of a new proteomics-based multibiomarker assay using caged amphipods

…, A Chaumot, A Charnot, C Almunia… - Environmental …, 2017 - ACS Publications
As a proof of principle, a selected reaction monitoring (SRM) mass spectrometry-based
methodology was applied to the simultaneous quantification of dozens of protein biomarkers in …

One NY-ESO-1-derived epitope that promiscuously binds to multiple HLA-DR and HLA-DP4 molecules and stimulates autologous CD4+ T cells from patients with NY …

M Mandic, F Castelli, B Janjic, C Almunia… - The Journal of …, 2005 - journals.aai.org
NY-ESO-1 is expressed by a broad range of human tumors and is often recognized by Abs
in the sera of cancer patients with NY-ESO-1-expressing tumors. The NY-ESO-1 gene also …

Proteogenomic insights into the core-proteome of female reproductive tissues from crustacean amphipods

J Trapp, C Almunia, JC Gaillard, O Pible, A Chaumot… - Journal of …, 2016 - Elsevier
As a result of the poor genome sequence coverage of crustacean amphipods, characterization
of their evolutionary biology relies mostly on phenotypic traits. Here, we analyzed the …

[HTML][HTML] Identification of immune-related proteins of Dreissena polymorpha hemocytes and plasma involved in host-microbe interactions by differential proteomics

M Leprêtre, C Almunia, J Armengaud, A Le Guernic… - Scientific reports, 2020 - nature.com
Biological responses of zebra mussel Dreissena polymorpha are investigated to assess the
impact of contaminants on aquatic organisms and ecosystems. In addition to concentrate …

Comparative proteomics in the wild: Accounting for intrapopulation variability improves describing proteome response in a Gammarus pulex field population exposed …

Y Cogne, C Almunia, D Gouveia, O Pible, A François… - Aquatic toxicology, 2019 - Elsevier
High-throughput proteomics can be performed on animal sentinels for discovering key
molecular biomarkers signing the physiological response and adaptation of organisms. …