Eukaryotic and archaeal translation initiation factor 2 (e/aIF2) is a heterotrimeric GTPase that
has a crucial role in the selection of the correct start codon on messenger RNA. We report …

Archaeal translation initiation occurs within a macromolecular complex containing the small
ribosomal subunit (30S) bound to mRNA, initiation factors aIF1, aIF1A and the ternary …

Translation initiation (TI) allows accurate selection of the initiation codon on a messenger
RNA (mRNA) and defines the reading frame. In all domains of life, translation initiation …

Eukaryotic and archaeal translation initiation processes involve a heterotrimeric GTPase e/aIF2
crucial for accuracy of start codon selection. In eukaryotes, the GTPase activity of eIF2 is …

In eukaryotes and in archaea late steps of translation initiation involve the two initiation
factors e/aIF5B and e/aIF1A. In eukaryotes, the role of eIF5B in ribosomal subunit joining is …

Eukaryotic and archaeal translation initiation complexes have a common structural core
comprising e/aIF1, e/aIF1A, the ternary complex (TC, e/aIF2-GTP-Met-tRNA i Met ) and mRNA …

The Arp2/3 complex generates branched actin networks that exert pushing forces onto
different cellular membranes. WASH complexes activate Arp2/3 complexes at the surface of …

Heterotrimeric eukaryotic/archaeal translation initiation factor 2 (e/aIF2) binds initiator
methionyl-tRNA and plays a key role in the selection of the start codon on messenger RNA. tRNA …

In eukaryotes and in archaea late steps of translation initiation involve the two initiation factors
e/aIF5B and e/aIF1A. These two factors are also orthologous to the bacterial IF2 and IF1 …

A critical consequence of the initiation of translation is the setting of the reading frame for
mRNA decoding. In eukaryotic and archaeal cells, heterotrimeric initiation factor e/aIF2, in its …