The recent emergence of multiple SARS‐CoV‐2 variants has caused considerable concern
due to both reduced vaccine efficacy and escape from neutralizing antibody therapeutics. It is…

Background: Intradermal injection of autologous serum elicits a wheal-and-flare response in
about 60% of patients with chronic idiopathic urticaria (CIU). This reactivity has been …

IgE Abs mediate allergic responses by binding to specific high affinity receptors (FcεRI) on
mast cells and basophils. Therefore, the IgE/FcεRI interaction is a target for clinical …

Obesity is a classified epidemic, increasing the risk of secondary diseases such as diabetes,
inflammation, cardiovascular disease, and cancer. The pleiotropic hormone leptin is the …

We have previously described a mouse monoclonal anti-human IgE antibody (BSW17)
capable of recognizing receptor-bound IgE without inducing mediator release from human …

The recent emergence of multiple SARS-CoV-2 variants has caused considerable concern
due to reduced vaccine efficacy and escape from neutralizing antibody therapeutics. It is …

According to Jerne’s network hypothesis, the binding site of an anti-idiotypic antibody also
represents the internal image of an epitope present on a foreign, or even a self antigen. In …

The Voltage-Gated Calcium Channel (VGCC) auxiliary subunit Cavα2δ-1 (CACNA2D1) is
the target/receptor of gabapentinoids which are known therapeutics in epilepsy and …

According to the network theory antibodies may act as antigens thus generating anti‐idiotypic
antibodies that can function as regulators of immune responses. Designed ankyrin repeat …

The peptide TAT-I24, composed of the 9-mer peptide I24 and the TAT (48-60) peptide, exerts
broad-spectrum antiviral activity against several DNA viruses. The current model of the …