Like most plasma membrane proteins, type I interferon (IFN) receptor (IFNAR) traffics from
the outer surface to the inner compartments of the cell. Long considered as a passive means …

The biology of the canine oocyte is unusual compared with that of other mammalian females.
The present paper reviews both in vivo and in vitro specificities of canine oocytes. Final …

This review reports existing and original data concerning the biology of the canine oocyte
and early embryo. It describes specific aspects of intra- and extra-follicular maturation of the …

In response to different types and intensities of mechanical force, cells modulate their
physical properties and adapt their plasma membrane (PM). Caveolae are PM nano-invaginations …

Understanding how membrane nanoscale organization controls transmembrane receptors
signaling activity remains a challenge. We studied interferon-γ receptor (IFN-γR) signaling in …

Caveolae are small invaginated pits that function as dynamic mechanosensors to buffer
tension variations at the plasma membrane. Here we show that under mechanical stress, the …

Caveolin-3 is the major structural protein of caveolae in muscle. Mutations in the CAV3 gene
cause different types of myopathies with altered membrane integrity and repair, expression …

Type-I interferons (IFNs) play a key role in the immune defences against viral and bacterial
infections, and in cancer immunosurveillance. We have established that clathrin-dependent …

Cells remodel their structure in response to mechanical strain. However, how mechanical
forces are translated into biochemical signals that coordinate the structural changes observed …

Tissue homeostasis requires regulation of cell–cell communication, which relies on signaling
molecules and cell contacts. In skin epidermis, keratinocytes secrete factors transduced by …