Neurofilament light chain (NfL) is a promising fluid biomarker of disease progression for
various cerebral proteopathies. Here we leverage the unique characteristics of the Dominantly …

Objective White matter hyperintensities (WMHs) are areas of increased signal on T2‐weighted
magnetic resonance imaging (MRI) scans that most commonly reflect small vessel …

… Author links open overlay panel Christoph Laske a b , Hamid R. Sohrabi c d , Shaun M. Frost
e f , Karmele López-de-Ipiña g , Peter Garrard h , Massimo Buscema i j , Justin Dauwels k , …

Alzheimer’s disease (AD) and normal pressure hydrocephalus (NPH) are common forms of
dementia in the elderly. Recent findings have suggested an involvement of brain-derived …

Importance Neurofibrillary tangles composed of aggregated tau protein are one of the
neuropathological hallmarks of Alzheimer disease (AD) and correlate with clinical disease severity…

The lack of readily available biomarkers is a significant hindrance toward progressing to
effective therapeutic and preventative strategies for Alzheimer's disease (AD). Blood-based …

BackgroundRepetitive transcranial magnetic stimulation (rTMS) has been proposed as a new
treatment option for depression. Previous studies were performed with low sample sizes in …

Major depression (MD) has been associated with decreased brain-derived neurotrophic
factor (BDNF) serum levels, while antidepressant drugs were found to increase these …

The neurotrophin brain-derived neurotrophic factor (BDNF) plays a critical role in neuronal
survival, synaptic plasticity, and memory. Several recent studies have demonstrated altered …

Background Nutrition is an important modifiable risk factor in Alzheimer's disease. Previous
trials of the multinutrient Fortasyn Connect showed benefits in mild Alzheimer's disease …