User profiles for Christoph Leuenberger

Christoph Leuenberger

University of Fribourg, Switzerland
Verified email at unifr.ch
Cited by 2608

Early farmers from across Europe directly descended from Neolithic Aegeans

…, M Unterländer, C Leuenberger… - Proceedings of the …, 2016 - National Acad Sciences
Farming and sedentism first appeared in southwestern Asia during the early Holocene and
later spread to neighboring regions, including Europe, along multiple dispersal routes. …

Efficient approximate Bayesian computation coupled with Markov chain Monte Carlo without likelihood

D Wegmann, C Leuenberger, L Excoffier - Genetics, 2009 - academic.oup.com
Approximate Bayesian computation (ABC) techniques permit inferences in complex
demographic models, but are computationally inefficient. A Markov chain Monte Carlo (MCMC) …

[HTML][HTML] ABCtoolbox: a versatile toolkit for approximate Bayesian computations

D Wegmann, C Leuenberger, S Neuenschwander… - BMC …, 2010 - Springer
Background The estimation of demographic parameters from genetic data often requires the
computation of likelihoods. However, the likelihood function is computationally intractable …

Analysis of ratios in multivariate morphometry

H Baur, C Leuenberger - Systematic Biology, 2011 - academic.oup.com
The analysis of ratios of body measurements is deeply ingrained in the taxonomic literature.
Whether for plants or animals, certain ratios are commonly indicated in identification keys, …

Bayesian computation and model selection without likelihoods

C Leuenberger, D Wegmann - Genetics, 2010 - academic.oup.com
Until recently, the use of Bayesian inference was limited to a few cases because for many
realistic probability models the likelihood function cannot be calculated analytically. The …

[PDF][PDF] Low prevalence of lactase persistence in Bronze Age Europe indicates ongoing strong selection over the last 3,000 years

…, J Orschiedt, U Brinker, A Scheu, C Leuenberger… - Current Biology, 2020 - cell.com
Lactase persistence (LP), the continued expression of lactase into adulthood, is the most
strongly selected single gene trait over the last 10,000 years in multiple human populations. It …

Taxon sampling and the optimal rates of evolution for phylogenetic inference

JP Townsend, C Leuenberger - Systematic Biology, 2011 - academic.oup.com
Optimal rates of evolution and the informativeness of characters for phylogenetic inference
have received increasing attention as the effort to distinguish phylogenetic signal and noise …

[BOOK][B] Symplectic Geometry: an Introduction based on the Seminar in Bern, 1992

B Aebischer, M Borer, M Kälin, C Leuenberger… - 2013 - books.google.com
The seminar Symplectic Geometry at the University of Berne in summer 1992 showed that
the topic of this book is a very active field, where many different branches of mathematics …

An approximate Markov model for the Wright–Fisher diffusion and its application to time series data

A Ferrer-Admetlla, C Leuenberger, JD Jensen… - Genetics, 2016 - academic.oup.com
The joint and accurate inference of selection and demography from genetic data is considered
a particularly challenging question in population genetics, since both process may lead to …

Inference of evolutionary jumps in large phylogenies using Lévy processes

P Duchen, C Leuenberger, SM Szilágyi… - Systematic …, 2017 - academic.oup.com
Although it is now widely accepted that the rate of phenotypic evolution may not necessarily
be constant across large phylogenies, the frequency and phylogenetic position of periods of …