Diverse inhibitory neurons in the mammalian brain shape circuit connectivity and dynamics
through mechanisms of synaptic plasticity. Inhibitory plasticity can establish excitation/…

Excitation in neural circuits must be carefully controlled by inhibition to regulate information
processing and network excitability. During development, cortical inhibitory and excitatory …

Adaptivity is a dynamical feature that is omnipresent in nature, socio-economics, and
technology. For example, adaptive couplings appear in various real-world systems, such as the …

Animals depend on fast and reliable detection of novel stimuli in their environment. Neurons
in multiple sensory areas respond more strongly to novel in comparison to familiar stimuli. …

In the brain, patterns of neural activity represent sensory information and store it in non‐random
synaptic connectivity. A prominent theoretical hypothesis states that assemblies, groups …

Synaptic changes are hypothesized to underlie learning and memory formation in the brain.
But Hebbian synaptic plasticity of excitatory synapses on its own is unstable, leading to …

Reproducible research and open science practices have the potential to accelerate scientific
progress by allowing others to reuse research outputs, and by promoting rigorous research …

Non-random connectivity can emerge without structured external input driven by activity-dependent
mechanisms of synaptic plasticity based on precise spiking patterns. Here we …

… Christoph Miehl is a PhD student supervised by Julijana Gjorgjieva at the Max Planck
Institute for Brain Research Frankfurt and the Technical University of Munich, Germany. He uses …

Objective: To assess the surgical and hardware complications in a series of 81 consecutive
patients undergoing subthalamic (STN) deep brain stimulation (DBS) for Parkinson disease (…