Acknowledgements We thank H. Pospiech, R. Smith, F. Grosse and S. Hasan for critical
reading of the manuscript and for help with the artwork. UH has been supported by the Swiss …

GABA B (γ-aminobutyric acid type B) receptors are important for keeping neuronal excitability
under control. Cloned GABA B receptors do not show the expected pharmacological …

RSAT (Regulatory Sequence Analysis Tools) is a modular software suite for the analysis of
cis-regulatory elements in genome sequences. Its main applications are (i) motif discovery, …

Structural biology, homology modelling and rational drug design require accurate three-dimensional
macromolecular coordinates. However, the coordinates in the Protein Data Bank (…

Synaptic plasticity in the autoassociative network of recurrent connections among hippocampal
CA3 pyramidal cells is thought to enable the storage of episodic memory. Impaired …

Curves+, a revised version of the Curves software for analyzing the conformation of nucleic
acid structures, is now available as a web server. This version, which can be freely accessed …

With the development of new experimental technologies, biologists are faced with an avalanche
of data to be computationally analyzed for scientific advancements and discoveries to …

The mechanisms governing the recruitment of functional glutamate receptors at nascent
excitatory postsynapses following initial axon-dendrite contact remain unclear. We examined …

Programs devoted to the analysis of protein sequences exist either as stand-alone programs
or as Web servers. However, stand-alone programs can hardly accommodate for the …

The cholinergic efferent inhibition of mammalian outer hair cells (OHCs) is mediated by a
hyperpolarizing K+ current. We have made whole- cell tight-seal recordings from single OHCs …