User profiles for Christophe E. Pierreux
 | Christophe PierreuxProfesseur UCLouvain Verified email at uclouvain.be Cited by 5317 |
Control of liver cell fate decision by a gradient of TGFβ signaling modulated by Onecut transcription factors
…, N Plumb-Rudewiez, CE Pierreux… - Genes & …, 2005 - genesdev.cshlp.org
During liver development, hepatocytes and biliary cells differentiate from common progenitors
called hepatoblasts. The factors that control hepatoblast fate decision are unknown. Here …
called hepatoblasts. The factors that control hepatoblast fate decision are unknown. Here …
Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9
BACKGROUND & AIMS: A number of diseases are characterized by defective formation of
the intrahepatic bile ducts. In the embryo, hepatoblasts differentiate to cholangiocytes, which …
the intrahepatic bile ducts. In the embryo, hepatoblasts differentiate to cholangiocytes, which …
Raf induces TGFβ production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells
K Lehmann, E Janda, CE Pierreux… - Genes & …, 2000 - genesdev.cshlp.org
c-Raf-1 is a major effector of Ras proteins, responsible for activation of the ERK MAP kinase
pathway and a critical regulator of both normal growth and oncogenic transformation. Using …
pathway and a critical regulator of both normal growth and oncogenic transformation. Using …
Transforming growth factor β-independent shuttling of Smad4 between the cytoplasm and nucleus
Smad4 plays a pivotal role in all transforming growth factor β (TGF-β) signaling pathways.
Here we describe six widely expressed alternatively spliced variants of human Smad4 with …
Here we describe six widely expressed alternatively spliced variants of human Smad4 with …
Plasticity of a transcriptional regulation network among alpha‐proteobacteria is supported by the identification of CtrA targets in Brucella abortus
AF Bellefontaine, CE Pierreux, P Mertens… - Molecular …, 2002 - Wiley Online Library
CtrA is a master response regulator found in many alpha‐proteobacteria. In Caulobacter
crescentus and Sinorhizobium meliloti, this regulator is essential for viability and is …
crescentus and Sinorhizobium meliloti, this regulator is essential for viability and is …
A feedback loop between the liver-enriched transcription factor network and miR-122 controls hepatocyte differentiation
BACKGROUND & AIMS: Hepatocyte differentiation is controlled by liver-enriched transcription
factors (LETFs). We investigated whether LETFs control microRNA expression during …
factors (LETFs). We investigated whether LETFs control microRNA expression during …
Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas
During pancreatic organogenesis endocrine cells arise from non self-renewing progenitors
that express Ngn3. The precursors that give rise to Ngn3 + cells are presumably located …
that express Ngn3. The precursors that give rise to Ngn3 + cells are presumably located …
Imprinting of the COPD airway epithelium for dedifferentiation and mesenchymal transition
…, B Weynand, MZ Ladjemi, CE Pierreux… - European …, 2015 - Eur Respiratory Soc
In chronic obstructive pulmonary disease (COPD), epithelial changes and subepithelial
fibrosis are salient features in conducting airways. Epithelial-to-mesenchymal transition (EMT) …
fibrosis are salient features in conducting airways. Epithelial-to-mesenchymal transition (EMT) …
The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse
CE Pierreux, AV Poll, CR Kemp, F Clotman… - Gastroenterology, 2006 - Elsevier
Background & Aims: A number of hereditary polycystic diseases are associated with formation
of cysts within the pancreatic ducts. The cysts result from abnormal tubulogenesis, but …
of cysts within the pancreatic ducts. The cysts result from abnormal tubulogenesis, but …
Bioprinting of a functional vascularized mouse thyroid gland construct
…, GA Frank, YD Khesuani, CE Pierreux… - …, 2017 - iopscience.iop.org
Bioprinting can be defined as additive biofabrication of three-dimensional (3D) tissues and
organ constructs using tissue spheroids, capable of self-assembly, as building blocks. The …
organ constructs using tissue spheroids, capable of self-assembly, as building blocks. The …