Apoptosis-detecting radioligands: current state of the art and future perspectives

…, N Steinmetz, C Van de Wiele… - European journal of …, 2004 - Springer
This review provides a critical and thorough overview of the radiopharmaceutical development
and in vivo evaluation of all apoptosis-detecting radioligands that have emerged so far, …

[HTML][HTML] Molecular imaging of hypoxia with radiolabelled agents

…, R Dierckx, C Vangestel, C Van de Wiele - European journal of …, 2009 - Springer
Tissue hypoxia results from an inadequate supply of oxygen (O 2 ) that compromises biological
functions. Structural and functional abnormalities of the tumour vasculature together with …

[HTML][HTML] Peptides as Quorum Sensing Molecules: Measurement Techniques and Obtained Levels In vitro and In vivo

…, C Van de Wiele, B De Spiegeleer - Frontiers in …, 2017 - frontiersin.org
The expression of certain bacterial genes is regulated in a cell-density dependent way, a
phenomenon called quorum sensing. Both Gram-negative and Gram-positive bacteria use this …

The effects of ARBs, ACEis, and statins on clinical outcomes of COVID-19 infection among nursing home residents

…, C Van De Wiele, F Vandaele, D Van Dijck… - Journal of the American …, 2020 - Elsevier
… f , Guy De Tré PhD d , Luc Belmans MD g , Richard Dobson PhD h , Evelien Wynendaele
PharmD, PhD a , Christophe Van De Wiele MD, PhD i , Filip Vandaele BSc j , Diemer Van Dijck …

Formatted anti–tumor necrosis factor α VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen …

…, E Beirnaert, H Jonckheere, CVD Wiele… - Arthritis & …, 2006 - Wiley Online Library
Objective The advent of tumor necrosis factor (TNF)–blocking drugs has provided rheumatologists
with an effective, but highly expensive, treatment for the management of established …

Technetium-99m RP527, a GRP analogue for visualisation of GRP receptor-expressing malignancies: a feasibility study

C Van de Wiele, F Dumont, R Vanden Broecke… - European journal of …, 2000 - Springer
Gastrin-releasing peptide (GRP) receptor scintigraphy could allow prediction of response to
GRP receptor-targeted treatment options, early non-invasive diagnosis and in vivo …

Predictors of overall and disease-free survival in metastatic castration-resistant prostate cancer patients receiving 225Ac-PSMA-617 radioligand therapy

…, T Lengana, FL Giesel, C Van de Wiele… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Metastatic prostate carcinoma overexpresses prostate-specific membrane antigen (PSMA),
making this antigen a suitable target for radioligand therapy of the disease. Here we report …

Predictive and prognostic value of metabolic tumour volume and total lesion glycolysis in solid tumours

C Van de Wiele, V Kruse, P Smeets… - European journal of …, 2013 - Springer
Data available in patients suffering from squamous cell carcinoma of the head and neck,
lung carcinoma, oesophageal carcinoma and gynaecological malignancies suggest that …

Dual time-point FDG PET/CT for differentiating benign from malignant solitary pulmonary nodules in a TB endemic area

…, A Maes, H Pottel, A Stoltz, C Van De Wiele - South African medical …, 2010 - journals.co.za
Objective. Fluorodeoxyglucose (FDG)-positron emission tomography (PET) is an accurate
non-invasive imaging test for differentiating benign from malignant solitary pulmonary nodules …

The immune system and cancer

D Loose, C Van de Wiele - Cancer Biotherapy and …, 2009 - liebertpub.com
Cancer patients mount adaptive immune responses against their tumor. However, while
tumor-infiltrating lymphocytes and natural-killer (NK) cells try to detect and eliminate malignant …